大肠杆菌复制基因dnaZX的核苷酸序列。
Nucleotide sequence of the Escherichia coli replication gene dnaZX.
作者信息
Yin K C, Blinkowa A, Walker J R
出版信息
Nucleic Acids Res. 1986 Aug 26;14(16):6541-9. doi: 10.1093/nar/14.16.6541.
Abstract
The Escherichia coli 2.2 kilobase dnaZX region contains one 1929 nucleotide reading frame which directs the synthesis of two protein products involved in DNA polymerization. The larger consists of 643 amino acids in a deduced 71,114 dalton chain which could be the tau subunit of DNA polymerase III. The smaller, the DNA polymerase III gamma subunit, is encoded by the same reading frame as the larger. The dnaZX sequence contains a region homologous to ATP binding sites, suggesting that these replication factors are adenine nucleotide binding proteins.
摘要
大肠杆菌2.2千碱基的dnaZX区域包含一个1929个核苷酸的阅读框，该阅读框指导合成参与DNA聚合的两种蛋白质产物。较大的一种由643个氨基酸组成，推导的链分子量为71,114道尔顿，可能是DNA聚合酶III的τ亚基。较小的一种，即DNA聚合酶IIIγ亚基，与较大的亚基由相同的阅读框编码。dnaZX序列包含一个与ATP结合位点同源的区域，这表明这些复制因子是腺嘌呤核苷酸结合蛋白。
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