Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA; Department of Neurology and Fixel Center for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Parkinsonism Relat Disord. 2019 Mar;60:167-170. doi: 10.1016/j.parkreldis.2018.08.026. Epub 2018 Sep 1.
Performance tasks are presumed to have greater validity than rating scales in assessing day-to-day behaviors in Parkinson's disease (PD). One such task is the revised Observed Tasks of Daily Living (OTDL-R), which has been used extensively in healthy older adults, and but not yet empirically examined in PD. Thus, the aims of the current study were to examine and determine the impact of cognitive, motor, and mood symptoms on OTDL-R performance in PD.
Nineteen non-demented PD patients and 18 healthy older adults (HC) were administered measures of mood and cognitive functioning, and the OTDL-R (subtests include medication and telephone use, and medication management). Clinical severity of PD was assessed using the H&Y stage, UPDRS, and Schwab and England functional disability scores.
Mann Whitney U tests indicated the PD patients were significantly slower to complete the OTDL-R and performed worse on only the telephone use subtest, relative to the HC group. In the PD group, hierarchical regression analyses revealed memory, attention, and initiative/perseveration were uniquely associated with the financial management subtest, after controlling for motor severity (ps < .05). No other significant relationships were found.
PD patients were slower to complete the OTDL-R, but only less accurate on the telephone use subtest. Poor performance on the telephone use subtest may be related to motor severity, while poor performance on the financial management subtest was related to attention and working memory. Overall, the findings warrant future investigation to determine the validity and reliability of the OTDL-R in PD.
与评定量表相比，绩效任务被认为在评估帕金森病（PD）患者的日常行为方面具有更高的有效性。其中一项任务是修订后的日常活动观察量表（OTDL-R），该量表已在健康老年人中广泛使用，但尚未在 PD 患者中进行实证检验。因此，本研究的目的是检验和确定认知、运动和情绪症状对 PD 患者 OTDL-R 表现的影响。
19 名非痴呆 PD 患者和 18 名健康老年人（HC）接受了情绪和认知功能测试，以及 OTDL-R（子测试包括药物和电话使用以及药物管理）。使用 H&Y 分期、UPDRS 和 Schwab 和 England 功能残疾评分评估 PD 的临床严重程度。
曼惠特尼 U 检验表明，PD 患者完成 OTDL-R 的速度明显较慢，且在电话使用子测试中的表现明显差于 HC 组。在 PD 组中，分层回归分析显示，在控制运动严重程度后（p<0.05），记忆、注意力和主动性/坚持性与财务管理子测试具有独特的相关性。没有发现其他显著关系。
PD 患者完成 OTDL-R 的速度较慢，但仅在电话使用子测试中的准确性较差。电话使用子测试的较差表现可能与运动严重程度有关，而财务管理子测试的较差表现则与注意力和工作记忆有关。总体而言，这些发现需要进一步研究以确定 OTDL-R 在 PD 中的有效性和可靠性。
