Roy-Chowdhuri Sinchita
Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard Unit 85, Houston, TX 77030, USA.
Surg Pathol Clin. 2018 Sep;11(3):669-677. doi: 10.1016/j.path.2018.04.007.
There has been a paradigm shift in the practice of cytopathology with the advent of highly sensitive molecular tests using small amounts of tissue that can provide diagnostic, prognostic, and predictive information for clinical management. The cytopathologist plays a key role in providing a timely and accurate diagnosis as well as ensuring appropriate processing and handling of the specimen and judicious triaging of the tissue for molecular testing that guide therapeutic decisions. As the era of "precision medicine" continues to evolve and expand, cytopathology remains a dynamic field with advances in the practice of molecular cytopathology providing new paradigms in clinical care.
随着使用少量组织的高灵敏度分子检测的出现，细胞病理学实践发生了范式转变，这些检测可为临床管理提供诊断、预后和预测信息。细胞病理学家在提供及时准确的诊断、确保标本的适当处理和处置以及明智地对组织进行分子检测分类以指导治疗决策方面发挥着关键作用。随着“精准医学”时代不断发展和扩大，细胞病理学仍然是一个充满活力的领域，分子细胞病理学实践的进展为临床护理提供了新的范式。
