恶性胸膜间皮瘤患者的血小板增多症。

Thrombocytosis in patients with malignant pleural mesothelioma.

作者信息

Nakano T, Fujii J, Tamura S, Hada T, Higashino K

出版信息

Cancer. 1986 Oct 15;58(8):1699-701. doi: 10.1002/1097-0142(19861015)58:8<1699::aid-cncr2820580820>3.0.co;2-b.

DOI:10.1002/1097-0142(19861015)58:8<1699::aid-cncr2820580820>3.0.co;2-b

PMID:3019510

Abstract

Thrombocytosis above 40.0 X 10(4)/mm3 occurred in five of six (83%) patients with malignant mesothelioma. In contrast, the incidence of thrombocytosis was 7.5% in patients with lung adenocarcinoma, 12.5% in squamous cell carcinoma, 5.1% in small cell carcinoma, and 41.7% in large cell carcinoma, respectively. The platelet count in large cell carcinoma was significantly higher than that in other cell types of lung cancer; however, the platelet count in malignant mesothelioma was much higher than that in large cell carcinoma. These results show that the incidence of thrombocytosis seems to be high in malignant mesothelioma, although the mechanism is thus far unknown.

摘要

在6例恶性间皮瘤患者中，有5例（83%）出现血小板计数高于40.0×10⁴/mm³的血小板增多症。相比之下，肺腺癌患者血小板增多症的发生率为7.5%，鳞状细胞癌患者为12.5%，小细胞癌患者为5.1%，大细胞癌患者为41.7%。大细胞癌患者的血小板计数显著高于其他类型的肺癌患者；然而，恶性间皮瘤患者的血小板计数远高于大细胞癌患者。这些结果表明，恶性间皮瘤中血小板增多症的发生率似乎较高，尽管其机制目前尚不清楚。