Karim Farida, Inam Hina, Choudry Usama Khalid, Hasnain Fatimi Saulat
Department of Opthalmology, Aga Khan University Hospital, Pakistan.
Department of Cardiothoracic surgery, Aga Khan University Hospital, Pakistan.
Int J Surg Case Rep. 2018;51:213-217. doi: 10.1016/j.ijscr.2018.08.051. Epub 2018 Aug 30.
Ectopic thyroid is rare, especially in the anterior mediastinum. Furthermore, true malignant transformation in ectopic location with normal orthotopic gland is exceptionally unusual. The authors have tried to put forward a challenging case of a malignant mediastinal mass managed successfully via a multidisciplinary approach.
We report the case of a 55 year old female with ectopic follicular variant of papillary thyroid cancer in the anterior mediastinum with no disease in the thyroid gland. Subsequently, complete excision of the mediastinal mass and total thyroidectomy was done followed by radio-iodine ablation with radiotherapy. Patient showed good uneventful recovery and remains tumor free till date.
The aim of this report is to bring forward malignant ectopic thyroid carcinoma as a differential for malignant mediastinal masses. It is emphasized that the diagnosis is made essentially through physical and pathological examination and, in most cases, only after surgery. A Multidisciplinary approach is recommended in such cases.
异位甲状腺很罕见,尤其是位于前纵隔的异位甲状腺。此外,在异位部位发生真正的恶性转化且原位甲状腺正常的情况极为罕见。作者试图提出一例具有挑战性的恶性纵隔肿块病例,该病例通过多学科方法成功治疗。
我们报告一例55岁女性,其前纵隔存在甲状腺乳头状癌的异位滤泡变体,而甲状腺未发现病变。随后,对纵隔肿块进行了完整切除并实施了全甲状腺切除术,接着进行了放射性碘消融及放疗。患者恢复良好,至今无肿瘤复发。
本报告的目的是提出恶性异位甲状腺癌作为恶性纵隔肿块的鉴别诊断。强调诊断主要通过体格检查和病理检查,且在大多数情况下,仅在手术后才能确诊。对于此类病例,建议采用多学科方法。