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异位甲状腺乳头状癌酷似远处转移组织。

Ectopic papillary thyroid carcinoma mimicking distant metastatic tissue.

机构信息

Department of Cardiothoracic Surgery, Chengde Central Hospital, No. 11 Guangren Road, Chengde, Hebei, People's Republic of China.

Department of Nephrology, Affiliated Hospital of Chengde Medical College, No. 36 Nanyingzi Street, Chengde, Hebei, People's Republic of China.

出版信息

J Int Med Res. 2022 Sep;50(9):3000605221121968. doi: 10.1177/03000605221121968.

DOI:10.1177/03000605221121968
PMID:36129883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9511341/
Abstract

We report a case of a 50-year-old woman presenting with a solid nodule in each lung. She was previously suspected of having lung cancer and distant pulmonary metastasis on the basis of imaging findings. Surgical pathology revealed that the left lung nodule was adenocarcinoma, but the contralateral nodule was papillary thyroid carcinoma (PTC). We subsequently performed total thyroidectomy, and the histological findings of the resected specimen showed no suspicious tumor tissue. Overall, the results led to a diagnosis of ectopic intrapulmonary PTC with synchronous lung adenocarcinoma. Ectopic intrapulmonary PTC is a rare but true phenomenon that may be easily mistaken for pulmonary metastasis in daily practice. It is important to improve the recognition of ectopic intrapulmonary thyroid tumors to avoid misdiagnosis.

摘要

我们报告了一例 50 岁女性,其每侧肺部均有一个实性结节。根据影像学发现,此前怀疑她患有肺癌和肺部远处转移。手术病理学显示左侧肺结节为腺癌,但对侧结节为甲状腺乳头状癌(PTC)。随后我们进行了甲状腺全切除术,切除标本的组织学检查结果显示无可疑肿瘤组织。总的来说,这些结果导致了异位性肺内 PTC 伴肺腺癌同步的诊断。异位性肺内 PTC 是一种罕见但真实的现象,在日常实践中可能很容易被误诊为肺转移。提高对异位性肺内甲状腺肿瘤的认识,避免误诊很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/8fe1d7d9223f/10.1177_03000605221121968-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/959874cf06e0/10.1177_03000605221121968-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/de06a5882aca/10.1177_03000605221121968-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/da4d45572572/10.1177_03000605221121968-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/8fe1d7d9223f/10.1177_03000605221121968-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/959874cf06e0/10.1177_03000605221121968-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/de06a5882aca/10.1177_03000605221121968-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/da4d45572572/10.1177_03000605221121968-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd5/9511341/8fe1d7d9223f/10.1177_03000605221121968-fig4.jpg

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Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.甲状腺癌:ESMO 诊断、治疗及随访临床实践指南†
Ann Oncol. 2019 Dec 1;30(12):1856-1883. doi: 10.1093/annonc/mdz400.
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Clinical characteristics and prognostic analysis of multiple primary malignant neoplasms in patients with lung cancer.
肺癌患者多原发恶性肿瘤的临床特征及预后分析。
Cancer Gene Ther. 2019 Nov;26(11-12):419-426. doi: 10.1038/s41417-019-0084-z. Epub 2019 Jan 31.
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Ectopic Papillary Thyroid Carcinoma Mimicking Esophageal Cancer in FDG PET: A Case Report.异位甲状腺乳头状癌在 FDG PET 中酷似食管癌:一例报告。
Clin Nucl Med. 2019 Jan;44(1):59-60. doi: 10.1097/RLU.0000000000002377.
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Ectopic thyroids have lower computed tomography attenuation values than orthotopic thyroids.异位甲状腺的 CT 衰减值低于正常甲状腺。
Endocrine. 2018 Dec;62(3):546-551. doi: 10.1007/s12020-018-1747-5. Epub 2018 Sep 10.
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Ectopic follicular variant of papillary thyroid carcinoma in anterior mediastinum with a normal thyroid gland. A case report.前纵隔甲状腺乳头状癌异位滤泡变体伴甲状腺正常。病例报告。
Int J Surg Case Rep. 2018;51:213-217. doi: 10.1016/j.ijscr.2018.08.051. Epub 2018 Aug 30.
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