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使用卷积神经网络对大鼠心脏进行超声分割

Ultrasound Segmentation of Rat Hearts Using Convolution Neural Networks.

作者信息

Dormer James D, Guo Rongrong, Shen Ming, Jiang Rong, Wagner Mary B, Fei Baowei

机构信息

Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA.

Department of Pediatrics, Emory University, Atlanta, GA.

出版信息

Proc SPIE Int Soc Opt Eng. 2018 Feb;10580. doi: 10.1117/12.2293558. Epub 2018 Mar 6.

Abstract

Ultrasound is widely used for diagnosing cardiovascular diseases. However, estimates such as left ventricle volume currently require manual segmentation, which can be time consuming. In addition, cardiac ultrasound is often complicated by imaging artifacts such as shadowing and mirror images, making it difficult for simple intensity-based automated segmentation methods. In this work, we use convolutional neural networks (CNNs) to segment ultrasound images of rat hearts embedded in agar phantoms into four classes: background, myocardium, left ventricle cavity, and right ventricle cavity. We also explore how the inclusion of a single diseased heart changes the results in a small dataset. We found an average overall segmentation accuracy of 70.0% ± 7.3% when combining the healthy and diseased data, compared to 72.4% ± 6.6% for just the healthy hearts. This work suggests that including diseased hearts with healthy hearts in training data could improve segmentation results, while testing a diseased heart with a model trained on healthy hearts can produce accurate segmentation results for some classes but not others. More data are needed in order to improve the accuracy of the CNN based segmentation.

摘要

超声被广泛用于诊断心血管疾病。然而,诸如左心室容积等估计目前需要手动分割,这可能很耗时。此外,心脏超声常常受到诸如阴影和镜像等成像伪像的影响,这使得基于简单强度的自动分割方法变得困难。在这项工作中,我们使用卷积神经网络(CNN)将嵌入琼脂模型中的大鼠心脏超声图像分割为四类:背景、心肌、左心室腔和右心室腔。我们还探讨了在一个小数据集中纳入一颗患病心脏如何改变结果。我们发现,将健康和患病数据结合起来时,平均总体分割准确率为70.0%±7.3%,而仅使用健康心脏时为72.4%±6.6%。这项工作表明,在训练数据中纳入患病心脏与健康心脏可以提高分割结果,而用在健康心脏上训练的模型测试患病心脏时,对于某些类别可以产生准确的分割结果,但对其他类别则不然。为了提高基于CNN的分割的准确性,还需要更多数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017f/6126353/43b0683bef7a/nihms-986995-f0001.jpg

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