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2015年肯尼亚普姆瓦尼妇产医院产前门诊孕妇的叶酸缺乏及叶酸强化面粉的使用情况

Folate deficiency and utilization of folic acid fortified flour among pregnant women attending antenatal clinic at Pumwani Maternity Hospital, Kenya, 2015.

作者信息

Mgamb Elizabeth, Gura Zeinab, Wanzala Peter, Githuku Jane, Makokha Anselimo

机构信息

Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.

Field Epidemiology and Laboratory Training Program-Kenya, Kenya.

出版信息

Pan Afr Med J. 2017 Nov 4;28(Suppl 1):8. doi: 10.11604/pamj.supp.2017.28.1.9296. eCollection 2017.

Abstract

INTRODUCTION

in 2012, the Government of Kenya amended the Food, Drug and Chemical Substances Act to make the fortification of maize and wheat flour with folic acid mandatory. We assessed folate deficiency, awareness and use of folic acid fortified flour among pregnant women receiving antenatal care (ANC) at a clinic at Pumwani Maternity Hospital, Kenya, 2015.

METHODS

we conducted a cross-sectional survey at Pumwani Maternity Hospital between October and November 2014. We enrolled pregnant women who received ANC and interviewed them using a semi-structured questionnaire after obtaining informed consent. Blood samples were collected from all study participants and serum folate level was analyzed by electrochemiluminescence immunoassay. Folate deficiency was defined as serum folate of < 10nmols/L and borderline folate deficiency was defined as serum folate of between 10nmols/L and 15nmols/L.

RESULTS

among the 247 study participants, two (1%) had folate deficiency. One hundred and seventy-nine (73.4%) had heard about folic acid, but only 56 (23%) had heard about folic acid fortified flour. Overall, 198 (80%) study participants consumed fortified brands of maize flour and 205 (84%) consumed fortified brands of wheat flour; only four (2%) and two (1%) of study participants consumed specific brands of maize and wheat flour respectively because they were fortified.

CONCLUSION

the prevalence of folate deficiency was low and this may have been because of the availability of fortification programs. Although there was limited knowledge of fortified flour, utilization was high. The Kenyan Ministry of Health should enforce implementation of the legislation on maize flour and wheat flour fortification by all milling industries.

摘要

引言

2012年,肯尼亚政府修订了《食品、药品和化学物质法案》,规定强制要求在玉米粉和小麦粉中添加叶酸。2015年,我们在肯尼亚普姆瓦尼妇产医院的一家诊所,对接受产前护理(ANC)的孕妇中叶酸缺乏情况、对叶酸强化面粉的知晓率及使用情况进行了评估。

方法

2014年10月至11月期间,我们在普姆瓦尼妇产医院开展了一项横断面调查。纳入接受产前护理的孕妇,在获得知情同意后,使用半结构化问卷对她们进行访谈。采集所有研究参与者的血样,采用电化学发光免疫分析法分析血清叶酸水平。叶酸缺乏定义为血清叶酸<10nmol/L,临界叶酸缺乏定义为血清叶酸在10nmol/L至15nmol/L之间。

结果

在247名研究参与者中,有两名(1%)存在叶酸缺乏。179名(73.4%)听说过叶酸,但只有56名(23%)听说过叶酸强化面粉。总体而言,198名(80%)研究参与者食用了强化品牌的玉米粉,205名(84%)食用了强化品牌的小麦粉;分别只有4名(2%)和2名(1%)研究参与者因面粉强化而食用特定品牌的玉米粉和小麦粉。

结论

叶酸缺乏的患病率较低,这可能是由于强化计划的实施。尽管对强化面粉的了解有限,但利用率较高。肯尼亚卫生部应强制所有制粉行业执行玉米粉和小麦粉强化的立法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3684/6125111/d42a56439784/PAMJ-SUPP-28-1-8-g001.jpg

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