• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

维生素A在免疫系统中的作用。

Role of Vitamin A in the Immune System.

作者信息

Huang Zhiyi, Liu Yu, Qi Guangying, Brand David, Zheng Song Guo

机构信息

Department of Pathology and Physiopathology, Guilin Medical University, Guilin 541004, Guangxi, China.

Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin 541004, Guangxi, China.

出版信息

J Clin Med. 2018 Sep 6;7(9):258. doi: 10.3390/jcm7090258.

DOI:10.3390/jcm7090258
PMID:30200565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6162863/
Abstract

Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body. VitA is known as an anti-inflammation vitamin because of its critical role in enhancing immune function. VitA is involved in the development of the immune system and plays regulatory roles in cellular immune responses and humoral immune processes. VitA has demonstrated a therapeutic effect in the treatment of various infectious diseases. To better understand the relationship between nutrition and the immune system, the authors review recent literature about VitA in immunity research and briefly introduce the clinical application of VitA in the treatment of several infectious diseases.

摘要

维生素A(VitA)是一种微量营养素,对于维持视力、促进生长发育以及保护体内上皮和黏液完整性至关重要。由于VitA在增强免疫功能方面的关键作用,它被称为抗炎维生素。VitA参与免疫系统的发育,并在细胞免疫反应和体液免疫过程中发挥调节作用。VitA在多种传染病的治疗中已显示出治疗效果。为了更好地理解营养与免疫系统之间的关系,作者回顾了近期关于VitA在免疫研究方面的文献,并简要介绍了VitA在几种传染病治疗中的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b209/6162863/c03484f9c7ed/jcm-07-00258-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b209/6162863/c03484f9c7ed/jcm-07-00258-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b209/6162863/c03484f9c7ed/jcm-07-00258-g001.jpg

相似文献

1
Role of Vitamin A in the Immune System.维生素A在免疫系统中的作用。
J Clin Med. 2018 Sep 6;7(9):258. doi: 10.3390/jcm7090258.
2
Cell-mediated and humoral immune responses in broiler chickens maintained on diets containing different levels of vitamin A.以含有不同水平维生素A的日粮饲养的肉鸡的细胞介导免疫反应和体液免疫反应。
Poult Sci. 1997 Oct;76(10):1368-78. doi: 10.1093/ps/76.10.1368.
3
Effects of Vitamin A on Immune Responses and Vitamin A Metabolism in Broiler Chickens Challenged with Necrotic Enteritis.维生素A对坏死性肠炎攻毒肉鸡免疫反应及维生素A代谢的影响
Life (Basel). 2023 May 1;13(5):1122. doi: 10.3390/life13051122.
4
Antenatal vitamin A administration attenuates lung hypoplasia by interfering with early instead of late determinants of lung underdevelopment in congenital diaphragmatic hernia.产前给予维生素A可通过干扰先天性膈疝肺发育不全的早期而非晚期决定因素来减轻肺发育不全。
J Pediatr Surg. 2005 Apr;40(4):658-65. doi: 10.1016/j.jpedsurg.2005.01.034.
5
Vitamin A Promotes the Repair of Mice Skeletal Muscle Injury through RARα.维生素 A 通过 RARα 促进小鼠骨骼肌损伤修复。
Nutrients. 2023 Aug 22;15(17):3674. doi: 10.3390/nu15173674.
6
Moderate vitamin A supplementation in obese mice regulates tissue factor and cytokine production in a sex-specific manner.适量补充维生素 A 可通过性别特异性方式调节肥胖小鼠组织因子和细胞因子的产生。
Arch Biochem Biophys. 2013 Nov 15;539(2):239-47. doi: 10.1016/j.abb.2013.06.020. Epub 2013 Jul 11.
7
Induction of vitamin A deficiency in turkeys.火鸡维生素A缺乏症的诱发
Avian Dis. 2000 Oct-Dec;44(4):809-17.
8
Enhanced stability and clinical absorption of a form of encapsulated vitamin A for food fortification.增强用于食物强化的包封维生素 A 形式的稳定性和临床吸收率。
Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2211534119. doi: 10.1073/pnas.2211534119. Epub 2022 Dec 12.
9
[Vitamin C and its physiological role with respect to the components of the immune system].[维生素C及其在免疫系统各组成部分方面的生理作用]
Vnitr Lek. 2012 Oct;58(10):743-9.
10
The role of micronutrient and immunomodulation effect in the vaccine era of COVID-19.在 COVID-19 的疫苗时代,微量营养素和免疫调节作用的作用。
J Chin Med Assoc. 2021 Sep 1;84(9):821-826. doi: 10.1097/JCMA.0000000000000587.

引用本文的文献

1
Scoping review of micronutrient imbalances, clinical manifestations, and interventions.微量营养素失衡、临床表现及干预措施的范围综述
World J Methodol. 2025 Dec 20;15(4):107664. doi: 10.5662/wjm.v15.i4.107664.
2
Micronutrient and protein-energy supplementation enhance vaccine responses in undernourished children: Evidence from a systematic review.微量营养素与蛋白质能量补充可增强营养不良儿童的疫苗反应:一项系统评价的证据
F1000Res. 2025 Jul 18;14:507. doi: 10.12688/f1000research.164227.3. eCollection 2025.
3
Evaluation of the Therapeutic Effect of Levamisole on Subclinical Mastitis in Bovine Leukemia Virus-Infected Cows Classified by Proviral Load.

本文引用的文献

1
[Effect of vitamin A as an adjuvant therapy for pneumonia in children: a Meta analysis].[维生素A作为儿童肺炎辅助治疗的效果:一项Meta分析]
Zhongguo Dang Dai Er Ke Za Zhi. 2018 Feb;20(2):146-153. doi: 10.7499/j.issn.1008-8830.2018.02.013.
2
All- Retinoic Acid Promotes an M1- to M2-Phenotype Shift and Inhibits Macrophage-Mediated Immunity to .全反式维甲酸促进M1型至M2型表型转变并抑制巨噬细胞介导的免疫反应。 (你提供的原文最后似乎不完整,少了一些内容)
Front Immunol. 2017 Nov 17;8:1560. doi: 10.3389/fimmu.2017.01560. eCollection 2017.
3
The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana.
按前病毒载量分类的牛白血病病毒感染奶牛亚临床乳腺炎中左旋咪唑治疗效果的评估
Animals (Basel). 2025 Jul 21;15(14):2145. doi: 10.3390/ani15142145.
4
Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse nematodes.计算机预测和基因分析表明,视黄酸调节是不同基因线虫中保守长寿途径的驱动因素。
bioRxiv. 2025 Jul 21:2024.10.23.619838. doi: 10.1101/2024.10.23.619838.
5
Association Between Vitamin A and D Status and the Risk of COVID-19 in the Elderly Population: A Single-Center Experience.老年人群中维生素A和D状态与新型冠状病毒肺炎风险的关联:单中心经验
J Inflamm Res. 2025 Jun 24;18:8233-8241. doi: 10.2147/JIR.S522566. eCollection 2025.
6
Metabolomics profiling of hypervitaminosis A in South African preschoolers is characterised by modified serum lysophospholipids and oxylipins.南非学龄前儿童维生素A过多症的代谢组学分析以血清溶血磷脂和氧化脂质的改变为特征。
Br J Nutr. 2025 Jun 14;133(11):1385-1394. doi: 10.1017/S0007114525103656. Epub 2025 Jun 17.
7
Nutritional Deficiencies and Oral Candidiasis in Children from Northeastern Romania: A Cross-Sectional Biochemical Assessment.罗马尼亚东北部儿童的营养缺乏与口腔念珠菌病:一项横断面生化评估
Nutrients. 2025 May 27;17(11):1815. doi: 10.3390/nu17111815.
8
Assessment of nutritional status among post-kala-azar dermal leishmaniasis patients in endemic areas of northern West Bengal, India.印度西孟加拉邦北部流行地区黑热病后皮肤利什曼病患者营养状况评估
Trop Parasitol. 2025 Jan-Jun;15(1):42-51. doi: 10.4103/tp.tp_47_24. Epub 2025 Apr 5.
9
Boosting Immunity Through Nutrition and Gut Health: A Narrative Review on Managing Allergies and Multimorbidity.通过营养与肠道健康增强免疫力:关于管理过敏和多种疾病的叙述性综述
Nutrients. 2025 May 15;17(10):1685. doi: 10.3390/nu17101685.
10
Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death.危重症患者营养摄入与营养不良的评估及其与28天死亡率的关系。
Sci Rep. 2025 May 5;15(1):15677. doi: 10.1038/s41598-025-00780-2.
在博茨瓦纳,微量营养素补充对HIV感染早期活动性结核病发病率的影响。
Nutr Diet Suppl. 2017;2017(9):37-45. doi: 10.2147/NDS.S123545. Epub 2017 Jul 14.
4
Effect of vitamin A and vitamin C supplementation on oxidative stress in HIV and HIV-TB co-infection at Lagos University Teaching Hospital (LUTH) Nigeria.尼日利亚拉各斯大学教学医院(LUTH)维生素A和维生素C补充剂对HIV及HIV与结核病合并感染时氧化应激的影响。
Afr Health Sci. 2017 Jun;17(2):308-314. doi: 10.4314/ahs.v17i2.3.
5
Mechanism underlying the suppressor activity of retinoic acid on IL4-induced IgE synthesis and its physiological implication.视黄酸对白细胞介素4诱导的IgE合成的抑制活性及其生理意义的潜在机制。
Cell Immunol. 2017 Dec;322:49-55. doi: 10.1016/j.cellimm.2017.10.001. Epub 2017 Oct 3.
6
Vitamin A supplements for reducing mother-to-child HIV transmission.用于降低母婴传播艾滋病毒的维生素A补充剂。
Cochrane Database Syst Rev. 2017 Sep 7;9(9):CD003648. doi: 10.1002/14651858.CD003648.pub4.
7
Low plasma vitamin A concentration is associated with tuberculosis in Moroccan population: a preliminary case control study.摩洛哥人群中低血浆维生素A浓度与结核病相关:一项初步病例对照研究。
BMC Res Notes. 2017 Aug 23;10(1):421. doi: 10.1186/s13104-017-2737-z.
8
Impact of Vitamin A and Carotenoids on the Risk of Tuberculosis Progression.维生素A和类胡萝卜素对结核病进展风险的影响。
Clin Infect Dis. 2017 Sep 15;65(6):900-909. doi: 10.1093/cid/cix476.
9
9-cis retinoic acid modulates the type I allergic immune response.9-cis 视黄酸调节 I 型过敏免疫反应。
J Allergy Clin Immunol. 2018 Feb;141(2):650-658.e5. doi: 10.1016/j.jaci.2017.03.046. Epub 2017 May 17.
10
Micronutrient supplementation in adults with HIV infection.对感染艾滋病毒的成年人进行微量营养素补充
Cochrane Database Syst Rev. 2017 May 18;5(5):CD003650. doi: 10.1002/14651858.CD003650.pub4.