Department of Food Science, Purdue University, West Lafayette, IN.
Diversey Inc., Charlotte, NC.
Am J Infect Control. 2019 Jan;47(1):27-32. doi: 10.1016/j.ajic.2018.07.005. Epub 2018 Sep 7.
Disinfectant towelettes are commonly used for surface disinfection to prevent health care-associated infections; however, there is limited consensus as to whether a surface needs to remain wet for the full label contact time after the disinfectant towelette has been used in order for complete efficacy to be achieved. The purpose of this study was to quantify the effect of contact time, including times before and after a product dries, on bactericidal efficacy of 6 towelette products registered by the Environmental Protection Agency .
Six disinfectant towelette products were tested at varying contact times, including defined label contact times. Quantitative Environmental Protection Agency MB-33-00 was used to measure disinfectant efficacy against Staphylococcus aureus on Formica. Complete dry time for each disinfectant was measured gravimetrically.
There were significant differences in dry times among the towelette products; contact time did not have a significant effect on bactericidal efficacy. There was no longitudinal effect when a disinfectant's contact time was greater than defined label contact time, irrespective of whether the product was wet or dry on the surface.
Overall, bactericidal efficacy varied by towelette product tested and surface area wiped. Wiping larger surface areas may lead to decreased bactericidal efficacy but is product dependent.
There was no additional bactericidal effect after a product dried, indicating that extended contact times beyond when the product dries will not enhance disinfection.
消毒湿巾常用于表面消毒,以预防与医疗保健相关的感染;然而,对于在使用消毒湿巾后,为了达到完全的功效,表面是否需要保持湿润达到标签规定的全部接触时间,目前尚未达成共识。本研究的目的是量化接触时间(包括产品干燥前后的时间)对美国环保署注册的 6 种湿巾产品杀菌功效的影响。
在不同的接触时间下(包括规定的标签接触时间)测试了 6 种消毒湿巾产品。使用定量的美国环保署 MB-33-00 方法在富美家防火板上测量对金黄色葡萄球菌的消毒效果。通过重量法测量每种消毒剂的完全干燥时间。
湿巾产品的干燥时间存在显著差异;接触时间对杀菌功效没有显著影响。当消毒剂的接触时间大于规定的标签接触时间时,无论表面是湿润还是干燥,都没有纵向效果。
总的来说,杀菌功效因测试的湿巾产品和擦拭的表面积而异。擦拭更大的表面积可能会导致杀菌功效降低,但这取决于产品。
产品干燥后没有额外的杀菌效果,这表明延长接触时间不会增强消毒效果。