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擦拭面积、产品类型和目标菌株会影响即用型消毒巾的杀菌效果。

Surface area wiped, product type, and target strain impact bactericidal efficacy of ready-to-use disinfectant Towelettes.

机构信息

1Department of Food Science, Purdue University, West Lafayette, IN 47907 USA.

2Diversey Inc., Charlotte, NC 28273 USA.

出版信息

Antimicrob Resist Infect Control. 2018 Oct 11;7:122. doi: 10.1186/s13756-018-0416-z. eCollection 2018.

DOI:10.1186/s13756-018-0416-z
PMID:30338060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6180426/
Abstract

BACKGROUND

Disinfectant products are often used on environmental surfaces (e.g. countertops, patient beds) and patient care equipment in healthcare facilities to help prevent the transmission of healthcare-associated infections. Ready-to-use (RTU) disinfectants in the form of pre-wetted towelettes are increasingly popular among healthcare facilities. Currently, the EPA does not require disinfectant manufacturers to include a recommended maximum surface area per towelette on their product labels. The objective of this study was to investigate the efficacy of disinfectant towelette products on a hard non-porous surface across different coverage areas using a quantitative EPA method. We hypothesized that there would be significant differences in the efficacy of disinfectant towelette products, and that the greater surface area(s) wiped would result in reduced bactericidal efficacy.

METHODS

This study tested ten disinfectant towelette products against strain ATCC CRM-6538 and strain ATCC 15442 on Formica surfaces. Defined surface areas were wiped and the towelette weighed before and after wiping to determine the amount of liquid released. Bactericidal efficacy testing was also performed after wiping following standard EPA protocols.

RESULTS

We found that disinfectant product, area of surface wiped, and strain impacted the bactericidal efficacy achieved. Disinfectant product type and area of surface wiped significantly impacted the percent of liquid released per ftfrom the towelette.

CONCLUSION

Overall, bactericidal efficacy varied by towelette product, surface area wiped, and strain. This study also found that wiping larger surface areas may lead to decreased bactericidal efficacy. Further research is needed to test its implication.

摘要

背景

消毒剂产品常用于医疗机构的环境表面（如台面、患者病床）和患者护理设备，以帮助预防医源性感染的传播。即用型（RTU）消毒湿巾在医疗机构中越来越受欢迎。目前，EPA 不要求消毒剂制造商在其产品标签上包含每片湿巾的建议最大表面积。本研究的目的是使用 EPA 定量方法研究不同覆盖面积下硬非多孔表面的消毒湿巾产品的功效。我们假设消毒湿巾产品的功效会有显著差异，擦拭的表面积越大，杀菌效果会降低。

方法

本研究使用 Formica 表面测试了十种消毒湿巾产品对 ATCC CRM-6538 菌株和 ATCC 15442 菌株的效果。擦拭规定的表面面积，在擦拭前后称重以确定释放的液体量。根据标准 EPA 协议，在擦拭后进行杀菌效力测试。

结果

我们发现消毒剂产品、擦拭的表面面积和菌株影响了达到的杀菌效果。消毒剂产品类型和擦拭的表面面积显著影响了每片湿巾释放的液体百分比。

结论

总体而言，杀菌效果因湿巾产品、擦拭的表面面积和菌株而异。本研究还发现，擦拭更大的表面面积可能会导致杀菌效果降低。需要进一步研究以测试其影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7f7/6180426/6cf6ed492aee/13756_2018_416_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7f7/6180426/6cf6ed492aee/13756_2018_416_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7f7/6180426/6cf6ed492aee/13756_2018_416_Fig1_HTML.jpg

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