Tulane University School of Medicine, New Orleans, LA.
Louisiana State University Health Sciences Center, New Orleans, LA.
Ethn Dis. 2018 Sep 6;28(Suppl 2):303-310. doi: 10.18865/ed.28.S2.303. eCollection 2018.
The Patient Centered Outcomes Research Institute (PCORI) supports patient-centered clinical comparative effectiveness research (CER) including health disparities and engagement portfolios. In 2013, PCORI launched the Pipeline to Proposal (P2P) mechanism to support development of novel patient- and stakeholder-centered partnerships focused on designing clinical CER funding proposals. By providing a tiered structure of successive small contracts and technical assistance, the P2P mechanism encourages development of new research partnerships among diverse stakeholders. As a comparatively new field, patient-centered outcomes research (PCOR) has few well-delineated methods for engaging patients and other non-scientists in effective teams with academics or clinicians to develop and implement rigorous, scientific research proposals. Community partnered participatory research (CPPR) provides a useful framework for structuring new partnerships. In this article we highlight the origins, development, and prospects of three current examples of funded P2P initiatives based in New Orleans and Los Angeles. We outline how these projects - Prisoner to Patient, the NOLA Partnership, and Resilience Among African American Men - use CPPR principles. We also describe how they have collaborated with, and contributed to, a two-way learning and knowledge exchange among members of the PCORI-funded Community and Patient Partnered Research Network. Lessons learned may be applicable to other groups planning to create new partnerships focused on implementing PCOR.
患者为中心的结局研究学会（PCORI）支持以患者为中心的临床对比效果研究（CER），包括健康差异和参与组合。2013 年，PCORI 启动了“从提案到项目”（P2P）机制，以支持以新颖的以患者和利益相关者为中心的伙伴关系为重点的设计临床 CER 资助提案。通过提供一系列连续的小合同和技术援助的分层结构，P2P 机制鼓励不同利益相关者之间发展新的研究伙伴关系。作为一个相对较新的领域，以患者为中心的结果研究（PCOR）在让患者和其他非科学家与学者或临床医生一起有效参与到团队中，以制定和实施严格的、科学的研究提案方面，方法寥寥无几。社区合作参与式研究（CPPR）为构建新的伙伴关系提供了一个有用的框架。本文重点介绍了基于新奥尔良和洛杉矶的三个当前资助的 P2P 倡议的起源、发展和前景。我们概述了这些项目——从囚犯到患者、新奥尔良伙伴关系和非裔美国男性的韧性——如何运用 CPPR 原则。我们还描述了它们如何与 PCORI 资助的社区和患者伙伴关系研究网络的成员进行合作，并为他们之间的双向学习和知识交流做出贡献。所吸取的经验教训可能适用于其他计划创建专注于实施 PCOR 的新伙伴关系的团体。
