Durrani Sajid, Akbar Shomaila, Heena Humariya
Medical Oncology, King Fahad Medical City, Riyadh, SAU.
Radiation Oncology, King Fahad Medical City, Riyadh, SAU.
Cureus. 2018 Jul 8;10(7):e2941. doi: 10.7759/cureus.2941.
Breast cancer remains the most common cancer in women. A diagnosis of cancer during pregnancy is uncommon. In recent decades, obstetricians are seeing an increasing number of women who become pregnant or desire to become pregnant after breast cancer treatment because of a delay in childbearing for a variety of reasons, including cultural, educational, and professional. Consequently, breast cancer in young women often occurs before the completion of reproductive plans. A discussion among the patient, the oncologist, and the obstetrician on the relative benefits of early delivery followed by treatment versus commencement of therapy while continuing the pregnancy is of utmost importance in order to reach a consensual decision. The best available evidence suggests that pregnancy after breast cancer increases the risk of recurrence. The birth outcome in women with a history of breast cancer is no different from that in the normal female population; however, increased risks of delivery complications have been reported in the literature. As concurrent pregnancy and breast cancer are uncommon, there are no data from large randomized trials; hence, recommendations are mainly based on retrospective studies.
乳腺癌仍然是女性中最常见的癌症。孕期被诊断出癌症的情况并不常见。近几十年来,由于包括文化、教育和职业等多种原因导致生育延迟,产科医生见到越来越多在乳腺癌治疗后怀孕或渴望怀孕的女性。因此,年轻女性的乳腺癌常常在生殖计划完成之前就发生了。患者、肿瘤学家和产科医生之间讨论早期分娩后再进行治疗与在继续妊娠的同时开始治疗各自的相对益处,对于达成共识性决定至关重要。现有最佳证据表明,乳腺癌后怀孕会增加复发风险。有乳腺癌病史的女性的分娩结局与正常女性群体并无不同;然而,文献报道了分娩并发症风险增加的情况。由于同时怀孕和患乳腺癌的情况并不常见,没有来自大型随机试验的数据;因此,建议主要基于回顾性研究。