Aoki K, Kawana R, Matsumoto I, Wadell G, de Jong J C
Jpn J Ophthalmol. 1986;30(2):158-64.
The clinical and etiological findings in 727 patients with viral conjunctivitis treated from January 1982 through December 1984 at Aoki Eye Clinic in Sapporo, Japan, were presented. The age of the patients ranged from 11 days to 88 years, and the monthly incidences of the disease from 18 to 131 cases, with a clustering in the summer season. The etiological diagnosis was established in 399 (54.9%) of the 727 patients: adenovirus (Ad) 3 in 45 cases; Ad4 in 98 cases; Ad8 in 57 cases; Ad19 in 23 cases; Ad37 in 51 cases; untyped Ad in 33 cases; enterovirus (EV) 70 in 60 cases; herpes simplex virus type I in 24 cases and varicella-zoster virus in 4 cases. The clinical pictures of adenovirus 37 conjunctivitis were generally similar to those of adenovirus 8 conjunctivitis, and subconjunctival hemorrhage was more frequently seen in cases of EV70 conjunctivitis. EV70 cases showed nosocomial infection. In addition to Ad8, Ad37 seems to play an important role as a causative agent of epidemic keratoconjunctivitis in Japan.
本文介绍了1982年1月至1984年12月期间在日本札幌青木眼科诊所接受治疗的727例病毒性结膜炎患者的临床和病因学研究结果。患者年龄从11天至88岁不等，每月发病例数在18至131例之间，且在夏季出现聚集性发病。727例患者中，399例（54.9%）确诊病因：腺病毒（Ad）3型45例；Ad4型98例；Ad8型57例；Ad19型23例；Ad37型51例；未分型腺病毒33例；肠道病毒（EV）70型60例；单纯疱疹病毒I型24例；水痘带状疱疹病毒4例。腺病毒37型结膜炎的临床表现与腺病毒8型结膜炎大致相似，而EV70型结膜炎患者结膜下出血更为常见。EV70型病例呈现医院感染。除Ad8型外，Ad37型似乎是日本流行性角膜结膜炎的重要致病原。
