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本文引用的文献

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Paternal diet programs offspring health through sperm- and seminal plasma-specific pathways in mice.父本饮食通过精子和精浆特异性途径调控后代健康。
Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10064-10069. doi: 10.1073/pnas.1806333115. Epub 2018 Aug 27.
2
Origins of lifetime health around the time of conception: causes and consequences.从受孕之时起塑造终生健康：成因与后果。
Lancet. 2018 May 5;391(10132):1842-1852. doi: 10.1016/S0140-6736(18)30312-X. Epub 2018 Apr 16.
3
Before the beginning: nutrition and lifestyle in the preconception period and its importance for future health.孕前：营养与生活方式及其对未来健康的重要性。
Lancet. 2018 May 5;391(10132):1830-1841. doi: 10.1016/S0140-6736(18)30311-8. Epub 2018 Apr 16.
4
Obesity or Overweight, a Chronic Inflammatory Status in Male Reproductive System, Leads to Mice and Human Subfertility.肥胖或超重，男性生殖系统中的一种慢性炎症状态，会导致小鼠和人类生育力低下。
Front Physiol. 2018 Jan 4;8:1117. doi: 10.3389/fphys.2017.01117. eCollection 2017.
5
The role of homocysteine in seminal vesicles remodeling in rat.同型半胱氨酸在大鼠精囊重塑中的作用。
Folia Histochem Cytobiol. 2017;55(2):62-73. doi: 10.5603/FHC.a2017.0010. Epub 2017 Jun 21.
6
Paternal low protein diet programs preimplantation embryo gene expression, fetal growth and skeletal development in mice.父本低蛋白饮食可调控小鼠着床前胚胎基因表达、胎儿生长和骨骼发育。
Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1371-1381. doi: 10.1016/j.bbadis.2017.02.009. Epub 2017 Feb 9.
7
A role for seminal plasma in modulating pregnancy outcomes in domestic species.精浆在调节家畜妊娠结局中的作用。
Reproduction. 2016 Dec;152(6):R223-R232. doi: 10.1530/REP-16-0313. Epub 2016 Sep 6.
8
Semen proteomics and male infertility.精液蛋白质组学与男性不育症
J Proteomics. 2017 Jun 6;162:125-134. doi: 10.1016/j.jprot.2016.08.018. Epub 2016 Aug 26.
9
Consumption of a high-fat diet alters the seminal fluid and gut microbiomes in male mice.食用高脂饮食会改变雄性小鼠的精液和肠道微生物群。
Reprod Fertil Dev. 2017 Aug;29(8):1602-1612. doi: 10.1071/RD16119.
10
Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder.精子 tsRNAs 导致获得性代谢紊乱的跨代遗传。
Science. 2016 Jan 22;351(6271):397-400. doi: 10.1126/science.aad7977. Epub 2015 Dec 31.

The remarkable legacy of a father's diet on the health of his offspring.

作者信息

Fleming Tom P

机构信息

Biological Sciences, Southampton General Hospital, University of Southampton, Southampton SO16 6YD, United Kingdom

出版信息

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):9827-9829. doi: 10.1073/pnas.1813731115. Epub 2018 Sep 14.

DOI:10.1073/pnas.1813731115
PMID:30217889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6176581/
Abstract
摘要