Key Laboratory of Functional Molecular Engineering of Guangdong Province, Guangdong Engineering Research Center for Green Fine Chemicals, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Org Biomol Chem. 2018 Oct 17;16(40):7315-7329. doi: 10.1039/c8ob01187g.
Cyclopropanes, one of the most important strained rings, have gained much attention for more than a century because of their interesting and unique reactivity. They not only exist in many natural products, but have also been widely used in the fields of organic synthesis, medicinal chemistry and materials science as versatile building blocks. Based on the sustainable development in this area, this review mainly focuses on the recent advances in the synthesis of cyclopropanes classified by the type of catalytic system, including regio-, diastereo-, and enantio-selective reactions.
环丙烷是最重要的张力环之一，由于其有趣而独特的反应性，一个多世纪以来一直受到广泛关注。它们不仅存在于许多天然产物中，而且还作为多功能构建块广泛应用于有机合成、药物化学和材料科学领域。基于这一领域的可持续发展，本文主要综述了按催化体系类型分类的环丙烷合成的最新进展，包括区域选择性、非对映选择性和对映选择性反应。
