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新型肢体成像设备的手-腕、膝和足-踝剂量学和图像质量测量,该设备提供 CBCT 和 2D 成像选择。

Hand-wrist, knee, and foot-ankle dosimetry and image quality measurements of a novel extremity imaging unit providing CBCT and 2D imaging options.

机构信息

Oral and Maxillofacial Radiology, University of North Carolina School of Dentistry, Chapel Hill, NC, 27599-7455, USA.

出版信息

Med Phys. 2018 Nov;45(11):4955-4963. doi: 10.1002/mp.13198. Epub 2018 Oct 10.

Abstract

PURPOSE

Radiation dose is a general concern in diagnostic imaging and a special concern for children who are at greater risk from radiation effects. This study evaluates effective doses (E) produced during 2D and volume imaging with a novel cone beam computed tomography (CBCT) based extremity imaging device. The device's compact size and protocol options offer image choices that enhance the potential for reduced dose and improved diagnostics when evaluating sports injuries.

METHODS

Hand-wrist, foot-ankle, and knee phantoms were developed for use with optically stimulated luminescent dosimeters (OSL). Dosimetry of transmission radiographs (2D) and CBCT volumes (3D) was assessed for Standard and lowered dose (Lite) exposure protocols. Effective dose was calculated for child and adult age groups. Image quality was assessed with contrast-to-noise ratio (CNR) and modulation transfer function (MTF). A figure of merit was calculated as the square of CNR divided by E.

RESULTS

Standard 2D doses ranged from 0.001-0.06 μSv for adults, 0.001-0.05 μSv for 15-yr olds, 0.003-0.13 μSv for 10-yr olds, and 0.005-0.20 for 5-yr olds. Dose reductions with Lite protocols ranged from 26 to 51%. Standard CBCT doses ranged from 0.3-4.6 μSv for adults, 0.3-4.4 μSv for 15-yr olds, 0.6-9.8 μSv for 10-yr olds, and 1-22.6 μSv for 5-yr olds. For both 2D and 3D a trend of increasing imaging dose with reduced age was present and was statistically significant for children below the age of 10 (P = 0.0009). Lite dose reductions averaged 47%. CNR was statistically reduced in Lite dose scans (P = 0.0384) but was not statistically different using FOM analysis (P = 0.3089). MTF was not significantly affected by the two dose protocols (P = 0.8104).

CONCLUSION

CBCT effective doses calculated from anthropomorphic phantom exposures following manufacturer suggested protocols appear to be substantially less than previously reported doses for similar MDCT extremity examinations. In this study, effective dose from 2D radiographic imaging was approximately two orders of magnitude less than CBCT imaging. Doses were on the order of a few minutes to hours of ubiquitous per-capita background dose for 2D imaging and a few hours to days for 3D imaging. Dose significantly increased for children younger than age 10. Lite protocols resulted in substantial dose reductions and can be recommended for children and those examinations where reduced CNR will not affect diagnosis. Flexibility of 2D and 3D imaging options with low-dose protocols make this technology a promising option for radiographic evaluation of the extremities. Efficacy studies are needed to determine when MDCT, CBCT or Digital Radiography are best used for particular diagnostic tasks.

摘要

目的

在诊断成像中,辐射剂量是一个普遍关注的问题,对于儿童来说,辐射效应的风险更大。本研究评估了一种新型基于锥形束计算机断层扫描(CBCT)的四肢成像设备在二维和容积成像中产生的有效剂量(E)。该设备的体积小,协议选项多样,可以在评估运动损伤时选择潜在的降低剂量和提高诊断效果的方案。

方法

为使用光激励发光剂量计(OSL),开发了手-腕、足-踝和膝关节模型。评估了标准和降低剂量(Lite)曝光方案下的透射射线照相(2D)和 CBCT 容积(3D)的剂量学。为儿童和成人年龄组计算了有效剂量。使用对比度噪声比(CNR)和调制传递函数(MTF)评估图像质量。将 CNR 的平方除以 E 计算出一个质量指标。

结果

标准 2D 剂量范围为成人 0.001-0.06 μSv、15 岁儿童 0.001-0.05 μSv、10 岁儿童 0.003-0.13 μSv 和 5 岁儿童 0.005-0.20 μSv。Lite 方案的剂量降低幅度为 26%至 51%。标准 CBCT 剂量范围为成人 0.3-4.6 μSv、15 岁儿童 0.3-4.4 μSv、10 岁儿童 0.6-9.8 μSv 和 5 岁儿童 1-22.6 μSv。对于 2D 和 3D,随着年龄的降低,成像剂量呈增加趋势,对于 10 岁以下的儿童,这种趋势具有统计学意义(P=0.0009)。Lite 剂量降低幅度平均为 47%。Lite 剂量扫描时 CNR 有统计学降低(P=0.0384),但使用 FOM 分析时无统计学差异(P=0.3089)。两种剂量方案对 MTF 无显著影响(P=0.8104)。

结论

根据制造商建议的方案,对人体模型进行锥形束 CT 有效剂量计算,结果表明,与类似的 MDCT 四肢检查相比,其有效剂量明显较低。在本研究中,2D 射线照相成像的有效剂量大约比 CBCT 成像低两个数量级。2D 成像的剂量为几分之一分钟到几小时,与普遍的人均背景剂量相当,而 3D 成像的剂量为几小时到几天。对于年龄小于 10 岁的儿童,剂量显著增加。Lite 方案可显著降低剂量,可推荐用于儿童和那些降低 CNR 不会影响诊断的检查。低剂量方案的 2D 和 3D 成像选项的灵活性使得该技术成为四肢射线照相评估的一个有前途的选择。需要进行疗效研究,以确定何时使用 MDCT、CBCT 或数字射线照相术最适合特定的诊断任务。

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