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对当前治疗意图的理解、与医疗服务提供者的沟通、对侵入性维持生命干预措施的偏好与决策冲突之间的关联:新加坡晚期心力衰竭患者的调查结果。

Associations between understanding of current treatment intent, communication with healthcare providers, preferences for invasive life-sustaining interventions and decisional conflict: results from a survey of patients with advanced heart failure in Singapore.

作者信息

Malhotra Chetna, Sim David, Jaufeerally Fazlur, Finkelstein Eric A

机构信息

Lien Centre for Palliative Care, Duke-NUS Medical School, Singapore.

National Heart Centre, Singapore.

出版信息

BMJ Open. 2018 Sep 19;8(9):e021688. doi: 10.1136/bmjopen-2018-021688.

Abstract

OBJECTIVES

To make informed choices about use of future invasive life-sustaining interventions (ILSI), patients with congestive heart failure (CHF) need to correctly understand the intent of their current treatments. However, healthcare providers may be wary of having these discussions due to fear of distressing patients. In this study, we assessed whether patients who understand their treatment intent are less willing to undergo ILSI and are indeed more psychologically distressed.

DESIGN, PARTICIPANTS AND OUTCOMES: As part of a cross-sectional survey conducted prior to randomising patients for a trial, we asked 282 patients with advanced CHF (New York Heart Association Class III and IV) whether they believe their existing treatments would cure their heart condition, their willingness to undergo ILSI and assessed their anxiety and depression using the Hospital Anxiety and Depression Scale.

RESULTS

Approximately half of patients reported a willingness to undergo ILSI if needed. Only 22% knew that their current treatments were not curative. These patients were far less willing to undergo ILSI (OR 0.28, 95% CI 0.15 to 0.56) and were not at a greater risk of having clinically significant anxiety (OR 0.72, 0.34 to 1.54) and depression (OR 0.70, 0.33 to 1.47) compared with those who did not understand their current treatment intent.

CONCLUSIONS

Improving patients' understanding of the intent of their current treatments can help patients make informed choices about ILSI.

TRIAL REGISTRATION NUMBER

NCT02299180; Pre-results.

摘要

目的

为了对未来侵入性生命维持干预措施(ILSI)的使用做出明智选择,充血性心力衰竭(CHF)患者需要正确理解其当前治疗的意图。然而,医疗保健提供者可能因担心让患者痛苦而对进行这些讨论有所顾虑。在本研究中,我们评估了了解治疗意图的患者是否不太愿意接受ILSI,以及他们在心理上是否确实更痛苦。

设计、参与者和结果:作为在将患者随机分组进行试验之前进行的横断面调查的一部分,我们询问了282例晚期CHF患者(纽约心脏协会III级和IV级),他们是否认为现有治疗能治愈其心脏病、他们接受ILSI的意愿,并使用医院焦虑和抑郁量表评估他们的焦虑和抑郁情况。

结果

约一半患者表示如有需要愿意接受ILSI。只有22%的患者知道他们目前的治疗无法治愈。与不了解当前治疗意图的患者相比,这些患者接受ILSI的意愿要低得多(比值比0.28,95%置信区间0.15至0.56),且临床上出现显著焦虑(比值比0.72,0.34至1.54)和抑郁(比值比0.70,0.33至1.47)的风险并不更高。

结论

提高患者对当前治疗意图的理解有助于患者对ILSI做出明智选择。

试验注册号

NCT02299180;预结果。

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