抗逆转录病毒抗体的结合导致体外逆转录病毒感染增加。
Increase of retroviral infection in vitro by the binding of antiretroviral antibodies.
作者信息
Legrain P, Goud B, Buttin G
出版信息
J Virol. 1986 Dec;60(3):1141-4. doi: 10.1128/JVI.60.3.1141-1144.1986.
Abstract
Monoclonal antiretrovirus antibodies were assayed for their ability to influence retrovirus infection in vitro. Some antibodies increased murine cell infection by an ecotropic virus and both murine and human cell infection by an amphotropic virus. The stability of these viruses was not modified, suggesting that antibody-virus complexes may be more infectious than free virus particles.
摘要
检测了单克隆抗逆转录病毒抗体在体外影响逆转录病毒感染的能力。一些抗体增加了嗜亲性病毒对鼠细胞的感染，以及双嗜性病毒对鼠细胞和人细胞的感染。这些病毒的稳定性未发生改变，这表明抗体 - 病毒复合物可能比游离病毒颗粒更具感染性。
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