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运动药理学:医学药理学家的视角

Sports Pharmacology: A Medical Pharmacologist's Perspective.

作者信息

Malve Harshad O

机构信息

Lead Medical Advisor, Medical Affairs, Novartis Healthcare Private Limited, Mumbai.

出版信息

J Pharm Bioallied Sci. 2018 Jul-Sep;10(3):126-136. doi: 10.4103/jpbs.JPBS_229_17.

Abstract

Abuse of substances or methods to enhance the performance is becoming very common in the sports, which often destroys the spirit of competition. The regulatory bodies for sports have reported rates ranging from 5% to 31% for the use of performance-enhancing substances among athletes. Athletes can have serious injuries and morbidities, leading to poor health with the use of such substances. Commonly abused agents in sports include anabolic-androgenic steroids and its analogs, blood, erythropoietin, growth hormone and its derivatives, nutritional supplements, creatine, amphetamines, beta-hydroxy-beta-methylbutyrate (HMB), stimulants, and analgesics. Health-care professionals need to be careful while prescribing medicines to sportspersons. Knowledge of exercise physiology, pharmacology of the commonly used agents for sports-related injuries, and agents used for doping could help the sportspersons and health-care professionals to avoid the embarrassment arising because of misuse of these agents. Sports pharmacology includes study of the various aspects of the drug use and abuse in sports and treatment of sports-related injuries. Focusing on sports pharmacology in the medical curriculum can help the upcoming health-care professionals to support the sportspersons to improve the quality of their life by using various drugs and other substances within the standardized limits and avoid embarrassment of doping.

摘要

滥用提高成绩的物质或方法在体育界正变得非常普遍,这常常破坏竞争精神。体育管理机构报告称,运动员中使用提高成绩物质的比例在5%至31%之间。运动员使用此类物质可能会受到严重伤害并引发疾病,导致健康状况不佳。体育界常见的滥用药物包括合成代谢雄激素类固醇及其类似物、血液、促红细胞生成素、生长激素及其衍生物、营养补充剂、肌酸、安非他明、β-羟基-β-甲基丁酸(HMB)、兴奋剂和镇痛药。医护人员在给运动员开药时需要谨慎。了解运动生理学、常用运动相关损伤药物的药理学以及用于兴奋剂的药物,有助于运动员和医护人员避免因滥用这些药物而产生的尴尬。运动药理学包括研究体育中药物使用和滥用的各个方面以及运动相关损伤的治疗。在医学课程中注重运动药理学可以帮助即将成为医护人员的人支持运动员在标准化限度内使用各种药物和其他物质来提高生活质量,并避免兴奋剂带来的尴尬。

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