Rehabilitation Department, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China,
Rehabilitation Department, Nanjing Drum Tower Hospital, The Affiliated Hospital of the Medical School at Nanjing University, Nanjing, Jiangsu, China.
Clin Interv Aging. 2018 Sep 11;13:1691-1700. doi: 10.2147/CIA.S163067. eCollection 2018.
Mild cognitive impairment (MCI) is known as a transitional stage or phase between normal aging and dementia. In addition, it is associated with an increased risk of dementia. Research has shown that moderate-intensity exercise is associated with a decreased risk of cognitive impairment. Two recent studies demonstrated that dance interventions are associated with improved cognitive function in the elderly with MCI.
We evaluated the effect of a moderate-intensity aerobic dance routine on the cognitive function in patients with MCI.
This is a single-blind randomized controlled trial. Sixty MCI patients were randomized to receive either treatment (aerobic dance routine + usual care) or control (usual care only) for 3 months. All patients received usual care for an additional 3 months thereafter. The aerobic dance routine was a specially designed dance routine which involved cognitive effort for patients to memorize the complex movements. Wechsler memory scale-revised logical memory (WMS-R LM) and event-related evoked potentials (ERPs) P300 latency were used to assess patients' cognitive function at baseline, 3 months, and 6 months.
Twenty-nine patients received exercise therapy and 31 patients received usual care. Patients in the treatment group showed a greater improvement in memory (difference in WMS-R LM changes over 3 months 4.6; 95% CI 2.2, 7.0; <0.001) and processing speed (difference in P300 latency changes over 6 months -20.0; 95% CI=-39.5, -0.4; <0.05) compared to control.
This dance routine improves cognitive function, especially episodic memory and processing speed, in MCI patients and merits promotion in communities.
轻度认知障碍（MCI）被认为是正常衰老和痴呆之间的过渡阶段或状态。此外，它与痴呆的风险增加有关。研究表明，中等强度的运动与认知障碍风险降低有关。最近的两项研究表明，舞蹈干预与改善 MCI 老年患者的认知功能有关。
我们评估了中等强度有氧运动对 MCI 患者认知功能的影响。
这是一项单盲随机对照试验。60 名 MCI 患者被随机分为治疗组（有氧运动+常规护理）或对照组（仅常规护理），治疗时间为 3 个月。所有患者在此后额外接受常规护理 3 个月。有氧运动是一种专门设计的舞蹈，患者需要记忆复杂的动作，以发挥认知作用。我们使用韦氏记忆量表修订版逻辑记忆（WMS-R LM）和事件相关诱发电位（ERPs）P300 潜伏期来评估患者在基线、3 个月和 6 个月时的认知功能。
29 名患者接受运动治疗，31 名患者接受常规护理。治疗组患者的记忆（3 个月时 WMS-R LM 变化差异 4.6；95%CI 2.2，7.0；<0.001）和处理速度（6 个月时 P300 潜伏期变化差异-20.0；95%CI=-39.5，-0.4；<0.05）改善更为明显。
这种舞蹈可以改善 MCI 患者的认知功能，特别是情景记忆和处理速度，值得在社区中推广。
