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BSACI 过敏性和非过敏性鼻炎诊断和管理指南(修订版 2017 年;第一版 2007 年)。

BSACI guideline for the diagnosis and management of allergic and non-allergic rhinitis (Revised Edition 2017; First edition 2007).

机构信息

The Royal National Throat Nose and Ear Hospital, London, UK.

UCLH NHS Foundation Trust, London, UK.

出版信息

Clin Exp Allergy. 2017 Jul;47(7):856-889. doi: 10.1111/cea.12953.

Abstract

This is an updated guideline for the diagnosis and management of allergic and non-allergic rhinitis, first published in 2007. It was produced by the Standards of Care Committee of the British Society of Allergy and Clinical Immunology, using accredited methods. Allergic rhinitis is common and affects 10-15% of children and 26% of adults in the UK, it affects quality of life, school and work attendance, and is a risk factor for development of asthma. Allergic rhinitis is diagnosed by history and examination, supported by specific allergy tests. Topical nasal corticosteroids are the treatment of choice for moderate to severe disease. Combination therapy with intranasal corticosteroid plus intranasal antihistamine is more effective than either alone and provides second line treatment for those with rhinitis poorly controlled on monotherapy. Immunotherapy is highly effective when the specific allergen is the responsible driver for the symptoms. Treatment of rhinitis is associated with benefits for asthma. Non-allergic rhinitis also is a risk factor for the development of asthma and may be eosinophilic and steroid-responsive or neurogenic and non- inflammatory. Non-allergic rhinitis may be a presenting complaint for systemic disorders such as granulomatous or eosinophilic polyangiitis, and sarcoidoisis. Infective rhinitis can be caused by viruses, and less commonly by bacteria, fungi and protozoa.

摘要

这是 2007 年首次发表的关于变应性和非变应性鼻炎的诊断和管理的更新指南。它是由英国过敏与临床免疫学学会标准护理委员会使用认可的方法制定的。变应性鼻炎很常见,在英国,10-15%的儿童和 26%的成年人受到影响,它会影响生活质量、上学和工作出勤率,并且是发展为哮喘的危险因素。变应性鼻炎通过病史和检查诊断,并辅以特定的过敏测试。中重度疾病的治疗选择是局部鼻腔皮质类固醇。鼻内皮质类固醇加鼻内抗组胺药联合治疗比单独使用任何一种药物更有效,是那些单药治疗控制不佳的鼻炎患者的二线治疗方法。当特定过敏原是引起症状的原因时,免疫疗法非常有效。鼻炎的治疗与哮喘的改善有关。非变应性鼻炎也是哮喘发展的危险因素,可能是嗜酸性粒细胞和类固醇反应性或神经源性和非炎症性。非变应性鼻炎可能是全身疾病如肉芽肿性或嗜酸性粒细胞性多血管炎和结节病的首发症状。感染性鼻炎可由病毒引起,较少由细菌、真菌和原生动物引起。

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