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等离子体生物传感

Plasmonic Biosensing.

机构信息

National Institute of Telecommunications (Inatel) , 37540-000 , Santa Rita do Sapucaí , MG , Brazil.

São Carlos Institute of Physics , University of São Paulo , CP 369, 13560-970 , São Carlos , SP , Brazil.

出版信息

Chem Rev. 2018 Oct 24;118(20):10617-10625. doi: 10.1021/acs.chemrev.8b00359. Epub 2018 Sep 24.

Abstract

Plasmonic biosensing has been used for fast, real-time, and label-free probing of biologically relevant analytes, where the main challenges are to detect small molecules at ultralow concentrations and produce compact devices for point-of-care (PoC) analysis. This review discusses the most recent, or even emerging, trends in plasmonic biosensing, with novel platforms which exploit unique physicochemical properties and versatility of new materials. In addition to the well-established use of localized surface plasmon resonance (LSPR), three major areas have been identified in these new trends: chiral plasmonics, magnetoplasmonics, and quantum plasmonics. In describing the recent advances, emphasis is placed on the design and manufacture of portable devices working with low loss in different frequency ranges, from the infrared to the visible.

摘要

等离子体生物传感已被用于快速、实时和无标记探测生物相关分析物,主要挑战是在超低浓度下检测小分子,并生产用于即时检测(POC)分析的紧凑型设备。本综述讨论了等离子体生物传感的最新趋势,甚至是新兴趋势,这些趋势利用了新材料的独特物理化学性质和多功能性。除了广泛应用的局域表面等离子体共振(LSPR)外,这些新趋势还确定了三个主要领域:手性等离子体学、磁等离子体学和量子等离子体学。在描述最新进展时,重点介绍了在不同频率范围内(从红外到可见)工作的具有低损耗的便携式设备的设计和制造。

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