Institute of Molecular Genetics of the ASCR, Vídeňská 1083, 142 20 Prague 4, Czech Republic.
Department of Human Evolutionary Biology, Institute of Anthropology, Faculty of Biology, Adam Mickiewicz University in Poznan, Umultowska 89, 61-614 Poznań, Poland.
Nucleic Acids Res. 2019 Jan 8;47(D1):D29-D32. doi: 10.1093/nar/gky843.
Ancient mitochondrial DNA is used for tracing human past demographic events due to its population-level variability. The number of published ancient mitochondrial genomes has increased in recent years, alongside with the development of high-throughput sequencing and capture enrichment methods. Here, we present AmtDB, the first database of ancient human mitochondrial genomes. Release version contains 1107 hand-curated ancient samples, freely accessible for download, together with the individual descriptors, including geographic location, radiocarbon dating, and archaeological culture affiliation. The database also features an interactive map for sample location visualization. AmtDB is a key platform for ancient population genetic studies and is available at https://amtdb.org.
古线粒体 DNA 因其在人群水平上的变异性而被用于追踪人类过去的人口事件。近年来,随着高通量测序和捕获富集方法的发展,已发表的古线粒体基因组数量有所增加。在这里,我们展示了 AmtDB,这是第一个古人类线粒体基因组数据库。发布版本包含 1107 个经过手工整理的古样本,可免费下载,同时还提供了包括地理位置、放射性碳测年和考古文化归属在内的个体描述符。该数据库还具有一个用于样本位置可视化的交互式地图。AmtDB 是古人群遗传研究的重要平台,可在 https://amtdb.org 上获得。