Kim Da Hyun, Min Byoung Jin, Jung Eun Jung, Byun Jung Mi, Jeong Dae Hoon, Lee Kyung Bok, Sung Moon Su, Kim Ki Tae, Kim Young Nam
Department of Obstetrics and Gynecology, Inje University Busan Paik Hospital, Busan, Korea.
Paik Institute for Clinical Research, Inje University Busan Paik Hospital, Busan, Korea.
Obstet Gynecol Sci. 2018 Sep;61(5):575-583. doi: 10.5468/ogs.2018.61.5.575. Epub 2018 Aug 9.
The purpose of this study was to evaluate the group B streptococcus (GBS) colonization rate in pregnant Korean women using selective culture media for GBS and to identify obstetrical complications and GBS-induced early-onset neonatal sepsis.
We evaluated 1,014 pregnant women who delivered at Busan Paik Hospital between January 2015 and December 2016. GBS colonization was assessed using chromID Strepto B agar. We evaluated GBS colonization in pregnant women, as well as the obstetrical complication and GBS-induced neonatal sepsis rates.
The total GBS colonization rate was 11.6% (117/1,014). No significant increase was observed in the rate of pregnancy-related complications between the GBS-positive and the GBS-negative groups. Among the 134 neonates born to colonized mothers, early neonatal sepsis was reported in 2 neonates (1.5%); however, these were cases of non-GBS-induced sepsis.
The GBS colonization rate (using selective culture media) in this study involving pregnant Korean women showed a higher colonization rate than that previously reported in Korea. Therefore, based on this study, we recommend GBS screening and the administration of intrapartum antibiotic prophylaxis in pregnant Korean women.
本研究旨在使用针对B族链球菌（GBS）的选择性培养基评估韩国孕妇的GBS定植率，并确定产科并发症及GBS引起的早发型新生儿败血症。
我们评估了2015年1月至2016年12月在釜山白医院分娩的1014名孕妇。使用chromID Strepto B琼脂评估GBS定植情况。我们评估了孕妇中的GBS定植情况，以及产科并发症和GBS引起的新生儿败血症发生率。
GBS总定植率为11.6%（117/1014）。GBS阳性组和GBS阴性组之间与妊娠相关的并发症发生率未观察到显著增加。在定植母亲所生的134名新生儿中，有2名新生儿（1.5%）报告发生早发型新生儿败血症；然而，这些均为非GBS引起的败血症病例。
本研究中涉及韩国孕妇的GBS定植率（使用选择性培养基）高于韩国此前报告的定植率。因此，基于本研究，我们建议对韩国孕妇进行GBS筛查并在分娩期给予抗生素预防性治疗。
