School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China.
Appl Microbiol Biotechnol. 2018 Dec;102(23):9873-9880. doi: 10.1007/s00253-018-9400-z. Epub 2018 Sep 25.
Microsclerotia (MS) consist of an outer layer of pigment parenchyma cells and an inner layer of colorless medulla cells. In nature, MS are formed as overwintering and spreading structures in phytopathogenic fungi. For biological applications, MS can be induced in artificial liquid medium. To understand the complicated structure of MS and molecular mechanism of MS development in entomopathogenic and phytopathogenic fungi, data from different studies can be integrated. In this review, the essential prerequisites, environmental cues, and internal stimulating factors for MS development are explored. Emerging knowledges about the association between transcriptional regulatory circuits and signaling pathways involved in MS development in entomopathogenic and phytopathogenic fungi is also highlighted.
小菌核由一层外色素薄壁细胞层和一层无色髓细胞层组成。在自然界中，小菌核是植物病原菌真菌越冬和传播的结构。在生物应用中，可以在人工液体培养基中诱导小菌核的形成。为了了解昆虫病原真菌和植物病原真菌中小菌核的复杂结构和发育的分子机制，可以整合来自不同研究的数据。在这篇综述中，探讨了小菌核发育的基本前提条件、环境线索和内部刺激因素。还强调了与昆虫病原真菌和植物病原真菌中小菌核发育相关的转录调控回路和信号通路之间的关联的新认识。
