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乌干达米德威诊所自愿接受 HIV 检测者中未确诊 HIV 感染和重新检测的相关因素。

Correlates of Undiagnosed HIV Infection and Retesting Among Voluntary HIV Testing Clients at Mildmay Clinic, Uganda.

机构信息

Division of Global HIV and Tuberculosis, US Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS-30, Atlanta, GA, 30333, USA.

Mildmay Clinic, Mildmay, Uganda.

出版信息

AIDS Behav. 2019 Apr;23(4):820-834. doi: 10.1007/s10461-018-2274-3.

DOI:10.1007/s10461-018-2274-3
PMID:30255386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6585440/
Abstract

Increasing HIV diagnosis is important for combatting HIV. We invited individuals aged ≥ 13 years seeking voluntary HIV testing at Mildmay Clinic in Uganda to undertake a computer or audio-computer-assisted self-interview to facilitate post-test counseling. We evaluated first-visit data from 12,233 consenting individuals between January 2011 and October 2013. HIV prevalence was 39.0%. Of those with HIV, 37.2% already knew they were infected. Undiagnosed infection was associated with not being single, screening positive for depression (aOR 1.16, 95% CI 1.04-1.28), and screening for harmful drinking behavior (aOR 1.23, 95% CI 1.10-1.39). The odds of retesting subsequent to HIV diagnosis were lower for males (aOR 0.80, 95% CI 0.70-0.92) and those screening positive for harmful drinking behavior (aOR 0.77, 95% CI 0.66-0.88). Retesting was also associated with higher education and perceived social status below 'better off'. Our findings reiterate the value of population-based HIV surveys to provide estimates of testing coverage.

摘要

提高 HIV 诊断率对于防治 HIV 至关重要。我们邀请了年龄在 13 岁及以上、在乌干达 Mildmay 诊所自愿接受 HIV 检测的人,让他们使用电脑或音频计算机辅助自我访谈来辅助检测后的咨询。我们评估了 2011 年 1 月至 2013 年 10 月期间 12233 名同意参与的个体的首次就诊数据。HIV 感染率为 39.0%。在这些 HIV 感染者中,37.2%的人已经知道自己感染了。未确诊的感染与非单身、抑郁筛查阳性(优势比 1.16,95%置信区间 1.04-1.28)和有害饮酒行为筛查阳性(优势比 1.23,95%置信区间 1.10-1.39)有关。男性(优势比 0.80,95%置信区间 0.70-0.92)和有害饮酒行为筛查阳性者(优势比 0.77,95%置信区间 0.66-0.88)随后进行 HIV 检测的可能性较低。较高的教育水平和认为自己的社会地位低于“较富裕”也与复筛有关。我们的研究结果重申了基于人群的 HIV 调查对提供检测覆盖估计的价值。

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