Bordoni Bruno, Morabito Bruno
Cardiology, Foundation Don Carlo Gnocchi (IRCCS)/Institute of Hospitalization and Care, Milano, ITA.
Osteopathy, School of Osteopathic Centre for Research and Studies, Rome, ITA.
Cureus. 2018 Jul 23;10(7):e3036. doi: 10.7759/cureus.3036.
Irritable bowel syndrome (IBS) is one of the most debilitating and common gastrointestinal disorders; nevertheless, its pathophysiology is still unclear. It affects 11% of the world's population, and is characterized by alternating periods of pain and/or motility disorders with periods of remission and without any evidence of any structural and functional organic variation. It has been recently proposed that an altered contractile ability of the diaphragm muscle might adversely influence intestinal motility. The text reviews the diaphragm's functions, anatomy, and neurological links in correlation with the presence of chronic symptoms associated to IBS, like chronic low back pain, chronic pelvic pain, chronic headache, and temporomandibular joint dysfunction, vagus nerve inflammation, and depression and anxiety. The interplay between an individual's breath dynamic and intestinal behaviour is still an unaddressed point in the physiopathology of IBS, and the paucity of scientific studies should recommend further research to better understand the importance of breathing in this syndrome.
肠易激综合征(IBS)是最使人衰弱且常见的胃肠道疾病之一;然而,其病理生理学仍不清楚。它影响着全球11%的人口,其特征是疼痛和/或动力障碍交替出现,伴有缓解期,且无任何结构和功能器质性改变的证据。最近有人提出,膈肌收缩能力的改变可能会对肠道动力产生不利影响。本文回顾了膈肌的功能、解剖结构以及与IBS相关的慢性症状(如慢性腰痛、慢性盆腔痛、慢性头痛和颞下颌关节功能障碍、迷走神经炎症以及抑郁和焦虑)之间的神经联系。个体呼吸动态与肠道行为之间的相互作用在IBS的病理生理学中仍是一个未解决的问题,科学研究的匮乏应促使进一步研究,以更好地理解呼吸在该综合征中的重要性。