Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands.
Rheumatology Department, School of Medicine, Universidad Militar Nueva Granada and Hospital Militar, Transversal 3 No. 49-00 3th floor, Bogotá, Colombia.
Clin Rheumatol. 2018 Nov;37(11):3063-3068. doi: 10.1007/s10067-018-4308-7. Epub 2018 Sep 26.
To validate a Spanish language translation of the ASAS Heath-Index (ASAS-HI) testing, its reliability, construct validity, and responsiveness in Colombian patients with spondyloarthritis. Translation was done following a forward-backward procedure. Patients fulfilling the Assessment of Spondyloarthritis international Society (ASAS) criteria for either axial or peripheral spondyloarthritis (SpA) participated. Test-retest reliability was assessed by intra-class correlation coefficient (ICC) in patients without treatment changes. In patients who required a therapeutic intervention, responsiveness was assessed using the standardized response mean (SRM). Construct validity was evaluated by Spearman correlation. Internal consistency (Cronbach's α) and discriminative ability of the ASAS-HI were assessed. Fifty patients were included: 54% male, mean (SD) age 44.8 (13.1), symptom duration 15.8 (9.7) years, Bath Ankylosing Spondylitis Disease Index (BASDAI) 4.6 (2.2), Bath Ankylosing Spondylitis Functioning Index (BASFI) 4.7 (2.5), Ankylosing Spondylitis Disease Activity Score with C-Reactive Protein (ASDAS-CRP) 2.2 (1.0). Axial SpA was established in 44 patients (ankylosing spondylitis (AS) = 30, non-radiographic axial SpA (nr-axSpA) = 14) and peripheral SpA in 6 patients. The score of the ASAS-HI was 8.2 (5.1). The test-retest reliability was good with an ICC of 0.84. SRM was 2.58 (1.75-3.37) in 10 patients with any intervention and 2.94 (2.13-4.24) for 7 patients starting TNF blockers. Construct validity showed a good correlation between ASAS-HI and pain, BASDAI, BASFI, and Ankylosing Spondylitis Disease Activity Score (ASDAS) (r ≥ 0.60). A high internal consistency was found with a Cronbach's α of 0.91. ASAS-HI discriminated well between patients with different stages of disease activity (BASDAI and ASDAS). Those with higher disease activity had higher ASAS-HI scores. The Spanish language translation of the ASAS-HI has proven to be psychometrically valid for Colombian patients with SpA. This version is available to evaluate the state of health and functioning in these patients and can be used in clinical practice.
为验证西班牙文版 ASAS 健康指数(ASAS-HI)在哥伦比亚脊柱关节炎患者中的翻译准确性、信度、结构效度和反应度,我们进行了正向-反向翻译。入组符合评估脊柱关节炎国际协会(ASAS)中轴或外周脊柱关节炎(SpA)标准的患者。无治疗改变的患者评估其测试-再测试信度,采用组内相关系数(ICC);需要治疗干预的患者采用标准化反应均值(SRM)评估反应度。结构效度采用 Spearman 相关性评估。评估 ASAS-HI 的内部一致性(Cronbach's α)和鉴别能力。共纳入 50 例患者:男性 54%,平均(标准差)年龄 44.8(13.1)岁,症状持续时间 15.8(9.7)年,Bath 强直性脊柱炎疾病活动指数(BASDAI)4.6(2.2),Bath 强直性脊柱炎功能指数(BASFI)4.7(2.5),C 反应蛋白-强直性脊柱炎疾病活动评分(ASDAS-CRP)2.2(1.0)。44 例患者中确立了中轴型 SpA(强直性脊柱炎(AS)=30 例,非放射学中轴型 SpA(nr-axSpA)=14 例),6 例患者为外周型 SpA。ASAS-HI 评分为 8.2(5.1)分。10 例患者接受任何干预时,测试-再测试信度良好,ICC 为 0.84;7 例开始使用 TNF 阻滞剂时,SRM 为 2.58(1.75-3.37)。结构效度显示 ASAS-HI 与疼痛、BASDAI、BASFI 和 ASDAS 之间具有良好相关性(r≥0.60)。Cronbach's α 为 0.91,内部一致性高。ASAS-HI 可很好地区分不同疾病活动度(BASDAI 和 ASDAS)患者。疾病活动度较高的患者 ASAS-HI 评分较高。西班牙文版 ASAS-HI 对哥伦比亚脊柱关节炎患者具有良好的心理测量学效度。该版本可用于评估这些患者的健康状况和功能,并可用于临床实践。