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《ASAS 健康指数在脊柱关节炎患者中的欧洲葡萄牙版本:测量特性》

The European Portuguese version of the ASAS Health Index for Patients with Spondyloarthritis: Measurement properties.

出版信息

Acta Reumatol Port. 2020 Jan-Mar;45(1):26-33.

Abstract

OBJECTIVE

The Assessments of SpondyloArthritis international Society Health Index (ASAS HI), estimates the impact of Spondyloarthritis (SpA) on global functioning and health. This article assesses the construct validity, reliability and responsiveness of the Portuguese version of the ASAS HI.

PATIENTS AND METHODS

Patients fulfilling ASAS classification criteria for axial (axSpA) or peripheral SpA (pSpA) were included. Construct validity was assessed through Spearman's correlation analysis with other health outcomes. Discriminant validity was tested comparing the ASAS HI across disease activity and functional states using the Kruskal-Wallis test. Internal consistency was assessed by Cronbach's α, and test-retest reliability by intraclass correlation coefficients (ICC). Responsiveness was evaluated by the standardized response mean (SRM) in patients with active disease who required therapy escalation.

RESULTS

Among the 91 patients included, 67% were male, mean (SD) age 47.2 (12.9) years, 63 patients with axSpA and 28 patients with pSpA. The hypothesis defined a priori to test construct validity were confirmed. The ASAS HI showed ability to discriminate between patients with different disease activity and functional states (p<0.001). Internal consistency (Cronbach's α: 0.88) and test-retest reliability [ICC=0.76 (95%CI 0.09-0.91)] were good. Responsiveness was moderate (SRM=-0.53). The smallest detectable change was 3.0.

CONCLUSIONS

The Portuguese version of the ASAS HI is a comprehensible questionnaire that is valid, reliable and responsive. It can be used to assess the impact of SpA and its treatment on functioning and health, in clinical practice and for research purposes.

摘要

目的

评估强直性脊柱炎国际学会健康指数(ASAS HI)评估强直性脊柱炎(SpA)对全球功能和健康的影响。本文评估了葡萄牙语版 ASAS HI 的结构有效性、可靠性和反应性。

患者和方法

符合 ASAS 轴性(axSpA)或外周 SpA(pSpA)分类标准的患者纳入本研究。通过 Spearman 相关分析评估结构有效性,与其他健康结果进行比较。使用 Kruskal-Wallis 检验比较疾病活动度和功能状态下的 ASAS HI,评估判别效度。采用 Cronbach's α 评估内部一致性,采用组内相关系数(ICC)评估重测信度。在需要治疗升级的活动期患者中,通过标准化反应均数(SRM)评估反应性。

结果

在纳入的 91 例患者中,67%为男性,平均(SD)年龄为 47.2(12.9)岁,63 例为 axSpA,28 例为 pSpA。预先定义的假设来检验结构有效性得到了验证。ASAS HI 能够区分不同疾病活动度和功能状态的患者(p<0.001)。内部一致性(Cronbach's α:0.88)和重测信度[ICC=0.76(95%CI 0.09-0.91)]良好。反应性为中度(SRM=-0.53)。最小可检测变化为 3.0。

结论

葡萄牙语版 ASAS HI 是一个易于理解的问卷,具有有效性、可靠性和反应性。它可用于评估 SpA 及其治疗对功能和健康的影响,适用于临床实践和研究目的。

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