Youn Un-Young, Shon Myung-Soo, Kim Gyo-Nam, Katagiri Riho, Harata Kaori, Kamegai Masayuki, Ishida Yasuyuki, Lee Seung-Cheol
1Department of Food Science and Biotechnology, Kyungnam University, Changwon, Gyeongnam, 51767 Korea.
2Department of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, Kasugai, 487-8501 Japan.
Food Sci Biotechnol. 2016 Aug 31;25(4):1183-1187. doi: 10.1007/s10068-016-0188-2. eCollection 2016.
Antioxidant and anti-adipogenic activities of water extract (WE) and methanol extract (ME) of acorn shells (AS), from Carruth. grown in Korea, were investigated. At a concentration of 50 μg/mL, the WE had a scavenging activity of 53.84% for the DPPH and 76.09% for the ABTS radical, while the ME had corresponding scavenging activities of 29.09 and 48.43%. Total phenolic contents of WE and ME were 375.96 and 288.01 mg gallic acid equivalents/g of extracts, respectively. Both extracts significantly inhibited 3T3-L1 adipogenesis in a dose-dependent manner, and concomitantly decreased the size and number of intracellular lipid droplets. Furthermore, the antiadipogenic activities of WE and ME are largely limited in the pre- and early stages of adipogenesis. The results suggest that AS may be a promising source of antioxidants and anti-obesity compounds.
对韩国种植的栎属植物的橡子壳水提取物（WE）和甲醇提取物（ME）的抗氧化和抗脂肪生成活性进行了研究。在浓度为50μg/mL时，水提取物对DPPH的清除活性为53.84%，对ABTS自由基的清除活性为76.09%，而甲醇提取物的相应清除活性分别为29.09%和48.43%。水提取物和甲醇提取物的总酚含量分别为375.96和288.01mg没食子酸当量/g提取物。两种提取物均以剂量依赖性方式显著抑制3T3-L1脂肪生成，并同时减少细胞内脂滴的大小和数量。此外，水提取物和甲醇提取物的抗脂肪生成活性在很大程度上局限于脂肪生成的前期和早期阶段。结果表明，橡子壳可能是抗氧化剂和抗肥胖化合物的一个有前景的来源。
