Department of Psychology, George Washington University, 2125 G Street NW, Washington, DC, 20052, USA.
Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
AIDS Behav. 2019 Jul;23(7):1737-1748. doi: 10.1007/s10461-018-2283-2.
Pre-exposure prophylaxis (PrEP) is an effective biomedical HIV prevention method. PrEP uptake has been persistently low among US women, particularly Black women, who account for 61% of new HIV diagnoses among women. Further understanding of barriers to Black women accessing PrEP is needed. This 2017 cross-sectional survey study explored race-based differences in PrEP interest and intention among women and the indirect association between race and comfort discussing PrEP with a healthcare provider through medical mistrust. The sample consisted of 501 adult women (241 Black; 260 White) who were HIV-negative, PrEP-inexperienced, and heterosexually active. Black women reported greater PrEP interest and intention than White women. However, Black women expressed higher levels of medical mistrust, which, in turn, was associated with lower comfort discussing PrEP with a provider. Medical mistrust may operate as a unique barrier to PrEP access among Black women who are interested in and could benefit from PrEP.
暴露前预防（PrEP）是一种有效的医学预防艾滋病毒感染的方法。在美国，女性，尤其是黑人女性，对 PrEP 的接受程度一直很低，而黑人女性占女性新诊断艾滋病病例的 61%。因此，需要进一步了解黑人女性获取 PrEP 的障碍。本 2017 年的横断面调查研究探讨了女性对 PrEP 兴趣和意愿的种族差异，以及通过医疗不信任与医疗服务提供者讨论 PrEP 的舒适度与种族之间的间接关联。该样本包括 501 名成年女性（241 名黑人；260 名白人），她们均为 HIV 阴性、无 PrEP 经验且异性恋活跃。黑人女性报告称对 PrEP 的兴趣和意愿大于白人女性。然而，黑人女性表示对医疗服务的不信任程度更高，而这种不信任反过来又与与提供者讨论 PrEP 的舒适度降低有关。医疗不信任可能是对 PrEP 感兴趣且可能从中受益的黑人女性获得 PrEP 的一个独特障碍。
