Andreola S, Audisio R A, Lombardi L
Tumori. 1986 Dec 31;72(6):609-16. doi: 10.1177/030089168607200612.
We describe two cases of fibrolamellar hepatocellular carcinoma of the liver in two young women. Both patients presented with diffuse intra-abdominal metastases; nevertheless they had a survival of 28 and 32 months, respectively, which sustains the better prognosis of this neoplasm. Electron microscopy of one case confirmed the oncocytic features of the neoplastic cells and showed intra- and intercellular duct-like vacuoles with numerous microvilli containing a microfilament core that terminated in a terminal web, which represents an unusual aspect in the spectrum of differentiation of fibrolamellar hepatocellular carcinoma.
我们描述了两名年轻女性患肝纤维板层状肝细胞癌的病例。两名患者均出现弥漫性腹腔内转移；然而，她们分别存活了28个月和32个月，这支持了该肿瘤较好的预后。其中一例的电子显微镜检查证实了肿瘤细胞的嗜酸性特征，并显示细胞内和细胞间有导管样空泡，有许多含有微丝核心的微绒毛，微丝核心终止于终末网，这在纤维板层状肝细胞癌的分化谱中是一个不寻常的表现。
