Kok Chin Yong, Chandrashekar Hoskote, Turner Christopher, Manji Hadi, Rossor Alexander M
MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK.
Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK.
Pract Neurol. 2019 Feb;19(1):72-74. doi: 10.1136/practneurol-2018-002016. Epub 2018 Oct 3.
Compressive lesions of the spinal cord usually cause a syndrome of upper motor neurone weakness, spasticity and sensory loss below the level of the lesion. It has long been recognised that compressive cervical cord lesions may present as isolated lower motor neurone weakness of the upper limbs, a syndrome termed cervical spondylotic amyotrophy. We describe two patients presenting with isolated lower motor neurone weakness of the lower limbs in association with a compressive cord lesion at T11/12, a condition we have termed thoracic spondylotic amyotrophy.
脊髓压迫性病变通常会导致病变水平以下出现上运动神经元性肌无力、痉挛和感觉丧失综合征。长期以来,人们已经认识到,颈椎脊髓压迫性病变可能表现为上肢孤立性下运动神经元性肌无力,这种综合征被称为颈椎病性肌萎缩。我们描述了两名患者,他们表现为下肢孤立性下运动神经元性肌无力,并伴有T11/12水平的脊髓压迫性病变,我们将这种情况称为胸椎病性肌萎缩。