Laboratory of Movement Analysis and Measurement Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Wearable Health Lab, Department of Orthopaedic Surgery, Stanford University, Redwood City, CA 94063, USA.
Sensors (Basel). 2018 Oct 3;18(10):3322. doi: 10.3390/s18103322.
Gait asymmetry is an important marker of mobility impairment post stroke. This study proposes a new gait symmetry index (GSI) to quantify gait symmetry with one 3D accelerometer at L3 (GSI). GSI was evaluated with 16 post stroke patients and nine healthy controls in the Six-Minute-Walk-Test (6-MWT). Discriminative power was evaluated with Wilcoxon test and the effect size (ES) was computed with Cliff's Delta. GSI estimated during the entire 6-MWT and during a short segment straight walk (GSI) have comparable effect size to one another (ES = 0.89, p < 0.001) and to the symmetry indices derived from feet sensors (|ES| = [0.22, 0.89]). Furthermore, while none of the indices derived from feet sensors showed significant differences between post stroke patients walking with a cane compared to those able to walk without, GSI was able to discriminate between these two groups with a significantly lower value in the group using a cane (ES = 0.70, p = 0.02). In addition, GSI was strongly associated with several symmetry indices measured by feet sensors during the straight walking cycles (Spearman correlation: |ρ| = [0.82, 0.88], p < 0.05). The proposed index can be a reliable and cost-efficient post stroke gait symmetry assessment with implications for research and clinical practice.
步态不对称是中风后运动障碍的一个重要标志物。本研究提出了一种新的步态对称指数(GSI),使用一个 L3 处的 3D 加速度计来量化步态对称。在六分钟步行测试(6-MWT)中,评估了 16 名中风后患者和 9 名健康对照者的 GSI。使用 Wilcoxon 检验评估判别能力,并计算 Cliff's Delta 的效应量(ES)。整个 6-MWT 期间和短段直线行走期间(GSI)估计的 GSI 具有相似的效应量(ES = 0.89,p < 0.001),与来自脚部传感器的对称指数(|ES| = [0.22,0.89])相当。此外,虽然来自脚部传感器的所有指数在使用拐杖行走的中风患者和能够不使用拐杖行走的患者之间均无显著差异,但 GSI 能够以使用拐杖的患者显著较低的价值来区分这两组(ES = 0.70,p = 0.02)。此外,GSI 与直线行走周期中来自脚部传感器的几个对称指数密切相关(Spearman 相关性:|ρ| = [0.82,0.88],p < 0.05)。该提出的指数可作为一种可靠且具有成本效益的中风后步态对称评估方法,对研究和临床实践具有重要意义。