Freymuth F, Quibriac M, Petitjean J, Pierre C, Duhamel J F, Denis A, Legoas C
Arch Fr Pediatr. 1986 Nov;43(9):677-9.
Human leucocytary interferon (IFN) in a concentration of 2,000 Ul/ml stops the development of 9 Rhinovirus (RV) strains. The use of serum IFN antibodies (SAIF) reverses this effect. Of 256 nasal aspirates culture negative for other respiratory viruses, 40 RV were isolated with SAIF as opposed to 19 without serum anti IFN. The frequency and some clinical aspects are emphasized in infants: 43% had bronchiolitis similar to respiratory syncytial virus (RSV) infections and atopy was frequent.
浓度为2000国际单位/毫升的人白细胞干扰素(IFN)可抑制9种鼻病毒(RV)毒株的生长。使用血清干扰素抗体(SAIF)可逆转这种作用。在256份对其他呼吸道病毒培养呈阴性的鼻吸出物中,使用SAIF分离出40株RV,而未使用血清抗干扰素的情况下分离出19株。文中强调了婴儿中的发生率及一些临床特征:43%的婴儿患有类似于呼吸道合胞病毒(RSV)感染的细支气管炎,且特应性情况很常见。