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本文引用的文献

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Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease.肝细胞核受体表达与儿童非酒精性脂肪性肝病的组织学特征相关。
Hepatol Commun. 2018 Sep 27;2(10):1213-1226. doi: 10.1002/hep4.1232. eCollection 2018 Oct.
2
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.全球 1975 年至 2016 年的体重指数、消瘦、超重和肥胖趋势:12890 万儿童、青少年和成年人 2416 项基于人群的测量研究的汇总分析。
Lancet. 2017 Dec 16;390(10113):2627-2642. doi: 10.1016/S0140-6736(17)32129-3. Epub 2017 Oct 10.
3
Nuclear receptors and nonalcoholic fatty liver disease.核受体与非酒精性脂肪性肝病
Biochim Biophys Acta. 2016 Sep;1859(9):1083-1099. doi: 10.1016/j.bbagrm.2016.03.002. Epub 2016 Mar 4.
4
Similarities and differences between pediatric and adult nonalcoholic fatty liver disease.儿童与成人非酒精性脂肪性肝病之间的异同
Metabolism. 2016 Aug;65(8):1161-71. doi: 10.1016/j.metabol.2016.01.008. Epub 2016 Jan 20.
5
Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening.依洛前列素,一种过氧化物酶体增殖物激活受体-α和-δ激动剂,可在不加重肝纤维化的情况下诱导非酒精性脂肪性肝炎消退。
Gastroenterology. 2016 May;150(5):1147-1159.e5. doi: 10.1053/j.gastro.2016.01.038. Epub 2016 Feb 11.
6
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial.法尼醇X核受体配体奥贝胆酸治疗非肝硬化、非酒精性脂肪性肝炎(FLINT):一项多中心、随机、安慰剂对照试验
Lancet. 2015 Mar 14;385(9972):956-65. doi: 10.1016/S0140-6736(14)61933-4. Epub 2014 Nov 7.
7
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease.过氧化物酶体增殖物激活受体 α(PPARα)作用的分子机制及其对非酒精性脂肪性肝病中脂质代谢、炎症和纤维化的影响。
J Hepatol. 2015 Mar;62(3):720-33. doi: 10.1016/j.jhep.2014.10.039. Epub 2014 Nov 1.
8
Pediatric nonalcoholic fatty liver disease: a multidisciplinary approach.小儿非酒精性脂肪性肝病:多学科诊疗模式。
Nat Rev Gastroenterol Hepatol. 2012 Jan 17;9(3):152-61. doi: 10.1038/nrgastro.2011.273.
9
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial.维生素E或二甲双胍治疗儿童和青少年非酒精性脂肪性肝病的效果:TONIC随机对照试验
JAMA. 2011 Apr 27;305(16):1659-68. doi: 10.1001/jama.2011.520.
10
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.吡格列酮、维生素 E 或安慰剂治疗非酒精性脂肪性肝炎。
N Engl J Med. 2010 May 6;362(18):1675-85. doi: 10.1056/NEJMoa0907929. Epub 2010 Apr 28.

Nuclear Receptors: Opening Up New Avenues of Pediatric Fatty Liver Research.

作者信息

Pandyarajan Vijay, Seki Ekihiro

机构信息

Division of Digestive and Liver Diseases, Department of Medicine Cedars-Sinai Medical Center Los Angeles CA.

出版信息

Hepatol Commun. 2018 Oct 1;2(10):1157-1159. doi: 10.1002/hep4.1260. eCollection 2018 Oct.

DOI:10.1002/hep4.1260
PMID:30288469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6167071/
Abstract
摘要