自杀风险与月经周期：候选 RDoC 机制综述。
Suicide Risk and the Menstrual Cycle: a Review of Candidate RDoC Mechanisms.
机构信息
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Psychiatry, Women's Mental Health Research Program, University of Illinois at Chicago, 912 S Wood St., South Tower, Room 335, Chicago, IL, 60612, USA.
出版信息
Curr Psychiatry Rep. 2018 Oct 6;20(11):106. doi: 10.1007/s11920-018-0962-3.
Abstract
PURPOSE OF REVIEW
Risk for suicidal behavior may fluctuate across the menstrual cycle. Here, we use the RDoC framework to review potential mechanisms by which the cycle may increase acute suicide risk.
RECENT FINDINGS
The menstrual cycle impacts the majority of RDoC constructs linked to suicide risk, particularly among hormone-sensitive women, such as those with premenstrual dysphoric disorder or premenstrual exacerbation of a psychiatric disorder. Despite this, there are no published studies examining suicidal ideation, planning, or behavior longitudinally across the cycle. More work is needed to understand how hormone sensitivity may relate to both trait and state suicide risk. Intensive multilevel investigations of cyclical hormone effects on suicide risk through specific RDoC mechanisms are suggested. This is a fertile research area and may provide key insights regarding the mechanisms of acute suicide risk.
摘要
目的综述
自杀行为的风险可能在月经周期中波动。在这里，我们使用 RDoC 框架来综述周期可能增加急性自杀风险的潜在机制。
最近的发现
月经周期影响与自杀风险相关的 RDoC 结构的大多数，尤其是在激素敏感的女性中，例如经前烦躁障碍或精神障碍经前恶化的女性。尽管如此，目前尚无研究在整个周期内纵向检查自杀意念、计划或行为。需要更多的工作来了解激素敏感性如何与特质和状态自杀风险相关。建议通过特定的 RDoC 机制对周期性激素对自杀风险的影响进行多层次的深入研究。这是一个富有成效的研究领域，可能为急性自杀风险的机制提供关键见解。
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