Nirmala College of Pharmacy, Mangalagiri, Guntur, Andhra Pradesh, India.
Research Officer, National Tea Research Foundation, Kolkata, India.
Biol Trace Elem Res. 2019 Jul;190(1):150-156. doi: 10.1007/s12011-018-1541-5. Epub 2018 Oct 7.
This research article aims to establish the intake ratio of probiotic Lactobacillus plantarum 299v with iron supplement pearl millet by central composite design of response surface methodology so as to enhance iron absorption. In anemic rat models, the food intake pattern, body weight, hemoglobin content, and hematocrit values were found to be significantly increased on treatment with pearl millet:probiotic; however, incorporation of probiotics at lower dose (0.5 g) was significantly (p < 0.05) effective in enhancing iron absorption, and further increment in probiotic doses (1.0 g) did not produce significant increase in hemoglobin and hematocrit values as evidenced by the experimental findings.
本研究文章旨在通过响应面法的中心复合设计来确定补充铁的珍珠粟与益生菌植物乳杆菌 299v 的摄入比例，以提高铁的吸收。在贫血大鼠模型中，发现用珍珠粟：益生菌处理后，食物摄入量、体重、血红蛋白含量和血细胞比容值显著增加；然而，低剂量（0.5g）的益生菌添加量在提高铁吸收方面具有显著效果（p<0.05），进一步增加益生菌剂量（1.0g）并没有像实验结果所证明的那样，显著增加血红蛋白和血细胞比容值。
