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安慰剂研究中的共识:来自科学哲学的教训

Consensus in Placebo Studies: Lessons from The Philosophy of Science.

作者信息

Blease Charlotte

出版信息

Perspect Biol Med. 2018;61(3):412-429. doi: 10.1353/pbm.2018.0053.

DOI:10.1353/pbm.2018.0053
PMID:30293979
Abstract

In the relatively nascent field of placebo studies, empirical studies have burgeoned. Yet debate about how to define the terms placebo and "placebo effect" has not abated. A number of prominent scholars (drawn from medical practice, as well as philosophy, psychology, and anthropology) continue to propose and defend different conceptual models for these terms, and the perception that conceptual debate persists is often given as one justification for new definitions. Paradoxically-in spite of this lively debate-this article finds considerable underlying agreement about definitional matters within placebo studies. Drawing on key insights from philosophy of science, and by exploring the nature of scientific consensus and normal scientific research, this paper argues that well-developed placebo concepts form the basis for a placebo paradigm and that conceptual disagreement is overstated.

摘要

在相对新兴的安慰剂研究领域,实证研究迅速发展。然而,关于如何定义“安慰剂”和“安慰剂效应”这两个术语的争论并未平息。许多杰出学者(来自医学实践、哲学、心理学和人类学)继续为这些术语提出并捍卫不同的概念模型,而概念性争论持续存在这一观点常常被用作新定义的一个理由。矛盾的是,尽管存在这场激烈的争论,但本文发现安慰剂研究在定义问题上存在相当多的潜在共识。借鉴科学哲学的关键见解,并通过探索科学共识和常规科学研究的本质,本文认为完善的安慰剂概念构成了安慰剂范式的基础,而且概念上的分歧被夸大了。

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引用本文的文献

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Putting the 'Art' Into the 'Art of Medicine': The Under-Explored Role of Artifacts in Placebo Studies.将“艺术”融入“医学艺术”:安慰剂研究中人工制品未被充分探索的作用。
Front Psychol. 2020 Jul 22;11:1354. doi: 10.3389/fpsyg.2020.01354. eCollection 2020.
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Primary care providers' use of and attitudes towards placebos: An exploratory focus group study with US physicians.初级保健提供者对安慰剂的使用和态度:一项美国医生的探索性焦点小组研究。
Br J Health Psychol. 2020 Sep;25(3):596-614. doi: 10.1111/bjhp.12429. Epub 2020 May 30.
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Placebos as a Source of Agency: Evidence and Implications.
安慰剂作为能动性的一个来源:证据与启示
Front Psychiatry. 2019 Oct 25;10:721. doi: 10.3389/fpsyt.2019.00721. eCollection 2019.
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Significance of Participants' Expectations in Managing the Placebo Effect in Antidepressant Research.参与者期望在抗抑郁研究中管理安慰剂效应的意义。
Front Psychiatry. 2019 Oct 1;10:713. doi: 10.3389/fpsyt.2019.00713. eCollection 2019.
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Placebo Effects in Psychotherapy: A Framework.心理治疗中的安慰剂效应:一个框架
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Re-evaluation of Significance and the Implications of Placebo Effect in Antidepressant Therapy.重新评估安慰剂效应在抗抑郁治疗中的意义及影响
Front Psychiatry. 2019 Mar 19;10:143. doi: 10.3389/fpsyt.2019.00143. eCollection 2019.
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When a Placebo Is Not a Placebo: Problems and Solutions to the Gold Standard in Psychotherapy Research.当安慰剂并非安慰剂时:心理治疗研究金标准中的问题与解决方案。
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