Advanced Clinical Biosystems Research Institute, The Smidt Heart Institute , Cedars Sinai Medical Center , Los Angeles , California 90048 , United States.
Department of Genetics , Stanford University School of Medicine , Stanford , California 94305 , United States.
J Proteome Res. 2019 Jan 4;18(1):1-6. doi: 10.1021/acs.jproteome.8b00504. Epub 2018 Oct 22.
It is now possible to collect large sums of health-related data which has the potential to transform healthcare. Proteomics, with its central position as downstream of genetics and epigenetic inputs and upstream of biochemical outputs and integrators of environmental signals, is well-positioned to contribute to health discoveries and management. We present our perspective on the role of proteomics and other Omics in precision health and medicine.
现在可以收集大量与健康相关的数据,这些数据有可能改变医疗保健。蛋白质组学作为遗传学和表观遗传学输入的下游,以及生化输出和环境信号整合器的上游,处于有利地位,可以为健康发现和管理做出贡献。我们提出了蛋白质组学和其他组学在精准健康和医学中的作用的观点。