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猫白血病病毒相关性肠炎——一种具有猫泛白细胞减少症特征的病症。

Feline leukemia virus-associated enteritis--a condition with features of feline panleukopenia.

作者信息

Reinacher M

出版信息

Vet Pathol. 1987 Jan;24(1):1-4. doi: 10.1177/030098588702400101.

DOI:10.1177/030098588702400101
PMID:3029936
Abstract

Infection with feline leukemia virus (FeLV) was demonstrated immunohistologically in 218 necropsied cats suffering from enteritis. The animals were divided into three groups according to histopathological criteria. The first group exhibited the signs of feline panleukopenia in intestine, lymphoid tissues, and bone marrow. Only 1.6% of these animals were FeLV-infected. The animals of the second group had histopathological alterations as seen in cats suffering from feline panleukopenia, but these were found only in the intestine and not in lymphoid tissues or bone marrow. Of these 71.9% were infected with FeLV. The third group consisted of all other cats suffering from enteritis of which 6.3% were FeLV-positive. The association between FeLV infection and the lesions seen in the animals of group 1 (feline panleukopenia) and group 3 (other types of enteritis) is statistically not significant whereas the alterations exhibited by the cats of group 2 are significantly FeLV-associated. Cats with FeLV-associated enteritis (group 2) are of a mean age of about 2.5 years and are significantly older than animals with feline panleukopenia which are of a mean age of about half a year. Thus a FeLV-associated enteritis exists as a histopathologically recognizable condition which sometimes might be mistaken for feline panleukopenia in routine post-mortem investigations.

摘要

通过免疫组织化学方法在218只患有肠炎的剖检猫中证实了猫白血病病毒(FeLV)感染。根据组织病理学标准将这些动物分为三组。第一组在肠道、淋巴组织和骨髓中表现出猫泛白细胞减少症的迹象。这些动物中只有1.6%感染了FeLV。第二组动物具有患猫泛白细胞减少症的猫所出现的组织病理学改变,但仅在肠道中发现,而在淋巴组织或骨髓中未发现。其中71.9%感染了FeLV。第三组包括所有其他患有肠炎的猫,其中6.3%的猫FeLV呈阳性。FeLV感染与第1组(猫泛白细胞减少症)和第3组(其他类型肠炎)动物所出现的病变之间的关联在统计学上不显著,而第2组猫所表现出的改变与FeLV显著相关。患有FeLV相关肠炎(第2组)的猫平均年龄约为2.5岁,明显比患有猫泛白细胞减少症的动物年龄大,后者平均年龄约为半年。因此,FeLV相关肠炎作为一种在组织病理学上可识别的病症存在,在常规尸检调查中有时可能会被误诊为猫泛白细胞减少症。

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