College of Life Sciences , Chongqing Normal University , No. 37 Chengzhong Road , Chongqing 401331 , People's Republic of China.
J Agric Food Chem. 2018 Oct 31;66(43):11209-11220. doi: 10.1021/acs.jafc.8b03210. Epub 2018 Oct 22.
Certain types of nanoparticles, especially zinc oxide nanoparticles (ZnONPs), are widely reported to be capable of the inhibition of harmful bacteria, yeasts, and filamentous fungi. The unique physicochemical and biological properties of ZnONPs also make them attractive to the food industry for use as a promising antifungal agent. This Review thoroughly introduces the preparation methods and antifungal properties of ZnONPs and analyzes their possible antifungal mechanisms. The applicability of ZnONPs in food packaging and nutritional supplements and as an antimicrobial additive is also documented. Moreover, evaluations for biological safety of ZnONPs are objectively reviewed in this paper. The discussions addressed in this Review not only have theoretical significance but also are conducive to the development of food safety, nutrition, and human health. The summarized knowledge and future perspectives outlined here are expected to promote and guide new research toward developing and optimizing the application of ZnONPs as a novel class of antifungal agents to help improve food quality as well as food safety in the near future.
某些类型的纳米粒子，尤其是氧化锌纳米粒子（ZnONPs），被广泛报道具有抑制有害细菌、酵母和丝状真菌的能力。ZnONPs 的独特物理化学和生物学特性也使它们成为食品工业有吸引力的抗真菌剂。本综述全面介绍了 ZnONPs 的制备方法和抗真菌特性，并分析了其可能的抗真菌机制。ZnONPs 在食品包装和营养补充剂以及作为抗菌添加剂中的应用也有记录。此外，本文还客观地评价了 ZnONPs 的生物安全性。本文讨论的内容不仅具有理论意义，而且有利于食品安全、营养和人类健康的发展。这里总结的知识和未来展望有望促进和指导新的研究，开发和优化 ZnONPs 作为一类新型抗真菌剂的应用，以帮助在不久的将来提高食品质量和食品安全。
