State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.
Nanoscale. 2018 Oct 18;10(40):19140-19146. doi: 10.1039/c8nr06162a.
Porous Co3O4 nanoplates were synthesized via a soft template method. By using amphiphilic block copolymer F127 colloids as the pore producer, porous Co(OH)2 nanoplates were prepared. After the annealing procedure, the obtained Co3O4 reserved the hexagonal shape and a similar size to the Co(OH)2 precursor. The as-prepared porous Co3O4 nanoplates named Co3O4-F simultaneously possessed peroxidase and catalase mimetic activities. Interestingly, these two kinds of mimetic enzyme activities could be switched by pH. Meanwhile, temperature and the concentrations of Co3O4-F had a significant effect on the switch pH and the dual-enzyme mimetic catalytic ability. Moreover, Co3O4-F exhibited good peroxidase-like catalytic activity even in the neutral pH system, providing a new strategy for one-step analysis of glucose. A novel one-step colorimetric glucose biosensor was fabricated based on the Co3O4-F nanozyme, making the operation of detection simpler and easier.
多孔 Co3O4 纳米板通过软模板法合成。通过使用两亲嵌段共聚物 F127 胶体作为孔产生剂，制备了多孔 Co(OH)2 纳米板。退火后，所得 Co3O4 保留了六方形状和与 Co(OH)2 前体相似的尺寸。所制备的多孔 Co3O4 纳米板命名为 Co3O4-F，同时具有过氧化物酶和过氧化氢酶模拟酶活性。有趣的是，这两种模拟酶活性可以通过 pH 值进行切换。同时，温度和 Co3O4-F 的浓度对切换 pH 值和双酶模拟催化能力有显著影响。此外，Co3O4-F 甚至在中性 pH 体系中也表现出良好的过氧化物酶样催化活性，为一步分析葡萄糖提供了新策略。基于 Co3O4-F 纳米酶构建了一种新型的一步比色葡萄糖生物传感器，使检测操作更加简单。
