韩国国内猪场中猪细小病毒7型的首次检测与基因特征分析
First detection and genetic characterization of porcine parvovirus 7 from Korean domestic pig farms.
作者信息
Ouh In-Ohk, Park Seyeon, Lee Ju-Yeon, Song Jae Young, Cho In-Soo, Kim Hye-Ryung, Park Choi-Kyu
机构信息
Viral Disease Research Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea.
College of Veterinary Medicine & Animal Disease Intervention Center, Kyungpook National University, Daegu 41566, Korea.
出版信息
J Vet Sci. 2018 Nov 30;19(6):855-857. doi: 10.4142/jvs.2018.19.6.855.
Porcine parvovirus 7 (PPV7) was first detected in Korean pig farms in 2017. The detection rate of PPV7 DNA was 24.0% (30/125) in aborted pig fetuses and 74.9% (262/350) in finishing pigs, suggesting that PPV7 has circulated among Korean domestic pig farms. Phylogenetic analysis based on capsid protein amino acid sequences demonstrated that the nine isolated Korean strains (PPV-KA1-3 and PPV-KF1-6) were closely related to the previously reported USA and Chinese PPV7 strains. In addition, the Korean strains exhibit genetic diversity with both insertion and deletion mutations. This study contributes to the understanding of the molecular epidemiology of PPV7 in Korea.
猪细小病毒7型（PPV7）于2017年首次在韩国猪场中被检测到。PPV7 DNA在流产仔猪中的检出率为24.0%（30/125），在育肥猪中的检出率为74.9%（262/350），这表明PPV7已在韩国国内猪场中传播。基于衣壳蛋白氨基酸序列的系统发育分析表明，9株分离的韩国毒株（PPV-KA1-3和PPV-KF1-6）与先前报道的美国和中国PPV7毒株密切相关。此外，韩国毒株表现出插入和缺失突变的遗传多样性。本研究有助于了解韩国PPV7的分子流行病学。
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