Suppr超能文献

非法重组发生在质粒pC194的复制起点与正在推进的复制叉之间。

Illegitimate recombination occurs between the replication origin of the plasmid pC194 and a progressing replication fork.

作者信息

Michel B, Ehrlich S D

出版信息

EMBO J. 1986 Dec 20;5(13):3691-6. doi: 10.1002/j.1460-2075.1986.tb04701.x.

Abstract

Hybrids between plasmids pC194, pBR322 and the bacteriophage f1 undergo deletions in Escherichia coli. The deletions end most often between nucleotides 1445 and 1446 of pC194. That site probably corresponds to a nick in the replication origin of this plasmid. The localization of the other deletion end appears to be determined by the position of the f1 replication fork. Two models accounting for these data are discussed.

摘要

质粒pC194、pBR322与噬菌体f1之间的杂种在大肠杆菌中会发生缺失。缺失大多在pC194的核苷酸1445和1446之间终止。该位点可能对应于该质粒复制起点处的一个切口。另一个缺失末端的定位似乎由f1复制叉的位置决定。文中讨论了两种解释这些数据的模型。

相似文献

2
Generation of deletions through a cis-acting mutation in plasmid pC194.
Mol Gen Genet. 1985;198(3):432-6. doi: 10.1007/BF00332935.
3
Rolling circle replication of single-stranded DNA plasmid pC194.单链DNA质粒pC194的滚环复制
EMBO J. 1987 Dec 1;6(12):3863-9. doi: 10.1002/j.1460-2075.1987.tb02724.x.
4
Illegitimate recombination at the replication origin of bacteriophage M13.噬菌体M13复制起点处的非法重组。
Proc Natl Acad Sci U S A. 1986 May;83(10):3386-90. doi: 10.1073/pnas.83.10.3386.
7
Deletion hot spots in chimeric Escherichia coli plasmids.嵌合型大肠杆菌质粒中的缺失热点
J Bacteriol. 1989 Apr;171(4):1846-53. doi: 10.1128/jb.171.4.1846-1853.1989.

引用本文的文献

2
Bacterial genome instability.细菌基因组不稳定性。
Microbiol Mol Biol Rev. 2014 Mar;78(1):1-39. doi: 10.1128/MMBR.00035-13.
5
Shuttle expression plasmids for genetic studies in Streptococcus mutans.用于变形链球菌基因研究的穿梭表达质粒。
Microbiology (Reading). 2008 Aug;154(Pt 8):2275-2282. doi: 10.1099/mic.0.2008/019265-0.

本文引用的文献

1
Sealing of gaps in duplex DNA by T4 DNA ligase.利用T4 DNA连接酶封闭双链DNA中的缺口。
Nucleic Acids Res. 1982 Mar 11;10(5):1425-37. doi: 10.1093/nar/10.5.1425.
3
Enzymatic synthesis of bacteriophage fd viral DNA.噬菌体fd病毒DNA的酶促合成
Nature. 1982 Apr 29;296(5860):828-32. doi: 10.1038/296828a0.
5
Site-specific recombination in the oriV1 region of the F factor.F因子oriV1区域的位点特异性重组。
Cold Spring Harb Symp Quant Biol. 1984;49:421-34. doi: 10.1101/sqb.1984.049.01.048.
9
Nucleotide sequence of bacteriophage f1 DNA.噬菌体f1 DNA的核苷酸序列。
J Virol. 1982 Oct;44(1):32-46. doi: 10.1128/JVI.44.1.32-46.1982.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验