Wiedemann Dominik, Haberl Thomas, Riebandt Julia, Simon Paul, Laufer Günther, Zimpfer Daniel
1. Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Eur Cardiol. 2014 Jul;9(1):54-58. doi: 10.15420/ecr.2014.9.1.54.
End-stage heart failure represents a substantial worldwide problem for the healthcare system. Despite significant improvements (medical heart failure treatment, implantable cardioverters, cardiac resyschronisation devices), long-term survival and quality of life of these patients remains poor. Heart transplantation has been an effective therapy for terminal heart failure, but it remains limited by an increasing shortage of available donor organs along with strict criteria defining acceptable recipients. For the last 50 years, mechanical alternatives to support the circulation have been investigated; however, during the early years device development has been marked in general by slow progress. However, in the past two decades, the technology has evolved dramatically. The purpose of this review is to give a short summary on the evolution of ventricular assist device (VAD) therapy and to give perspectives for future treatment of heart failure.
终末期心力衰竭是全球医疗系统面临的一个重大问题。尽管有了显著改善（如心力衰竭的药物治疗、植入式心脏复律器、心脏再同步化装置），但这些患者的长期生存率和生活质量仍然很差。心脏移植一直是治疗终末期心力衰竭的有效方法，但由于可用供体器官日益短缺以及定义可接受受者的严格标准，其应用仍然受到限制。在过去的50年里，人们一直在研究支持循环的机械替代方法；然而，在早期，设备开发总体上进展缓慢。然而，在过去的二十年里，这项技术有了巨大的发展。本综述的目的是简要总结心室辅助装置（VAD）治疗的发展历程，并展望心力衰竭的未来治疗前景。
