Powell Jeffrey R
Yale University, 21 Sachem Street, New Haven, CT 06520-8105, USA.
Insects. 2018 Oct 11;9(4):139. doi: 10.3390/insects9040139.
The issue of typological versus population thinking in biology is briefly introduced and defined. It is then emphasized how population thinking is most relevant and useful in vector biology. Three points are made: (1) Vectors, as they exist in nature, are genetically very heterogeneous. (2) Four examples of how this is relevant in vector biology research are presented: Understanding variation in vector competence, GWAS, identifying the origin of new introductions of invasive species, and resistance to inbreeding. (3) The existence of high levels of vector genetic heterogeneity can lead to failure of some approaches to vector control, e.g., use of insecticides and release of sterile males (SIT). On the other hand, vector genetic heterogeneity can be harnessed in a vector control program based on selection for refractoriness.
简要介绍并定义了生物学中类型学思维与群体思维的问题。接着强调了群体思维在病媒生物学中如何最为相关且有用。提出了三点：（1）自然界中存在的病媒在基因上具有很大的异质性。（2）给出了这在病媒生物学研究中相关的四个例子：理解病媒传播能力的变异、全基因组关联研究（GWAS）、确定入侵物种新引入的来源以及对近亲繁殖的抗性。（3）病媒高度的基因异质性的存在可能导致某些病媒控制方法失败，例如使用杀虫剂和释放不育雄虫（昆虫不育技术）。另一方面，基于对难治性的选择，病媒基因异质性可被用于病媒控制项目中。
