（有性型）再生障碍性贫血患者念珠菌血症：病例报告
(teleomorph ) candidaemia in a patient with aplastic anaemia: a case report.
作者信息
Treguier Pauline, David Marion, Gargala Gilles, Camus Vincent, Stamatoullas Aspasia, Menard Anne-Lise, Lenain Pascal, Contentin Nathalie, Lemasle Emilie, Lanic Helene, Tilly Hervé, Jardin Fabrice, Lepretre Stéphane
机构信息
INSERM U1245, Department of Hematology, Centre Henri Becquerel, Université of Rouen Normandie, Rouen, France.
Laboratory of Microbiology, Centre Henri Becquerel, Rouen, France.
出版信息
JMM Case Rep. 2018 Jul 10;5(8):e005160. doi: 10.1099/jmmcr.0.005160. eCollection 2018 Aug.
INTRODUCTION
We present what is believed to be the first report of candidaemia caused by () (teleomorph of ) in a patient with an aplastic anaemia.
CASE PRESENTATION
The patient, a 21-year-old male, presented with hepatic cytolysis, cutaneous and pulmonary involvement, and septic shock. was identified by aerobic blood culture and MS. The patient initially received multiple and combined antifungal therapy, but continued to have persistent skin lesions and fever. He was successfully treated by emergency haploidentical haematopoietic stem cell transplantation, combined with triple antifungal therapy and supportive care.
CONCLUSION
, teleomorph of , which is not usually invasive, can lead to an opportunistic invasive infection in unhealthy adult patients. For treatment of the invasive candida infection, it is necessary to combine antifungal therapy and supportive care.
引言
我们报告了一例再生障碍性贫血患者由（）（的有性型）引起的念珠菌血症，据信这是首例此类报告。
病例介绍
该患者为一名21岁男性，表现为肝细胞溶解、皮肤和肺部受累以及感染性休克。通过需氧血培养和质谱分析法鉴定出（）。患者最初接受了多种联合抗真菌治疗，但皮肤病变和发热持续存在。通过紧急单倍体相合造血干细胞移植，联合三联抗真菌治疗和支持治疗，患者最终成功治愈。
结论
通常不具有侵袭性的的有性型可导致不健康成年患者发生机会性侵袭性感染。对于侵袭性念珠菌感染的治疗，有必要联合抗真菌治疗和支持治疗。
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