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The influence of the charge and of the tin-ligand ratio on bone uptake of technetium 99m labelled osteotropic radiopharmaceuticals.

作者信息

Gouaillardou D, Conti M L

出版信息

Int J Rad Appl Instrum A. 1987;38(2):103-6. doi: 10.1016/0883-2889(87)90004-9.

DOI:10.1016/0883-2889(87)90004-9
PMID:3032858
Abstract

This work describes the determination of the charge for various 99mTc-Sn-phosphonate complexes. The variation of the Sn/P ratio using an HMDP ligand produces complexes with different negative charges. Biological distribution studies show superior bone uptake of strongly negative charged complexes.

摘要

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Int J Rad Appl Instrum A. 1987;38(2):103-6. doi: 10.1016/0883-2889(87)90004-9.
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